ENSMUSG00000028926


Mus musculus

Features
Gene ID: ENSMUSG00000028926
  
Biological name :Cdk14
  
Synonyms : Cdk14 / Cyclin-dependent kinase 14 / O35495
  
Possible biological names infered from orthology : O94921
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: A1
Gene start: 4803391
Gene end: 5420312
  
Corresponding Affymetrix probe sets: 10527940 (MoGene1.0st)   1419249_at (Mouse Genome 430 2.0 Array)   1419250_a_at (Mouse Genome 430 2.0 Array)   1453956_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114741
Ensembl peptide - ENSMUSP00000111111
Ensembl peptide - ENSMUSP00000130895
Ensembl peptide - ENSMUSP00000111112
Ensembl peptide - ENSMUSP00000030763
Ensembl peptide - ENSMUSP00000111110
NCBI entrez gene - 18647     See in Manteia.
MGI - MGI:894318
RefSeq - XM_017320708
RefSeq - XM_006503544
RefSeq - XM_006503547
RefSeq - NM_001310448
RefSeq - NM_011074
RefSeq Peptide - NP_035204
RefSeq Peptide - NP_001297377
swissprot - O35495
swissprot - Q6NVF8
swissprot - E9Q9M2
swissprot - D3YV23
swissprot - E9PVC7
Ensembl - ENSMUSG00000028926
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdk14ENSDARG00000074665Danio rerio
 CDK14ENSGALG00000009062Gallus gallus
 CDK14ENSG00000058091Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cdk15 / Q3V3A1 / Cyclin-dependent kinase 15 / Q96Q40*ENSMUSG0000002602351
Cdk17 / Q8K0D0 / Cyclin-dependent kinase 17 / Q00537*ENSMUSG0000002001545
Cdk18 / Q04899 / Cyclin-dependent kinase 18 / Q07002*ENSMUSG0000002643745
Cdk16 / Q04735 / Cyclin-dependent kinase 16 / Q00536*ENSMUSG0000003106545


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle ISS
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0060828 regulation of canonical Wnt signaling pathway ISS
 cellular_componentGO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004693 cyclin-dependent protein serine/threonine kinase activity ISO
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030332 cyclin binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004647 decreased lumbar vertebrae number "reduced number of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MESH:National Library of Medicine_Medical Subject Headings]
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Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd

 MP:0010101 increased sacral vertebrae number "increase of any or all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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