ENSMUSG00000031065


Mus musculus

Features
Gene ID: ENSMUSG00000031065
  
Biological name :Cdk16
  
Synonyms : Cdk16 / Cyclin-dependent kinase 16 / Q04735
  
Possible biological names infered from orthology : Q00536
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: A1.3
Gene start: 20687954
Gene end: 20699880
  
Corresponding Affymetrix probe sets: 10598912 (MoGene1.0st)   1415956_a_at (Mouse Genome 430 2.0 Array)   1438314_at (Mouse Genome 430 2.0 Array)   1438625_s_at (Mouse Genome 430 2.0 Array)   1443296_at (Mouse Genome 430 2.0 Array)   1460169_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000033380
Ensembl peptide - ENSMUSP00000111021
NCBI entrez gene - 18555     See in Manteia.
MGI - MGI:97516
RefSeq - XM_017318425
RefSeq - NM_001310456
RefSeq - NM_011049
RefSeq - XM_006527570
RefSeq - XM_017318424
RefSeq Peptide - NP_001297385
RefSeq Peptide - NP_035179
swissprot - Q3TM24
swissprot - Q543G3
swissprot - Q04735
Ensembl - ENSMUSG00000031065
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdk16ENSDARG00000032072Danio rerio
 CDK16ENSG00000102225Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cdk17 / Q8K0D0 / Cyclin-dependent kinase 17 / Q00537*ENSMUSG0000002001570
Cdk18 / Q04899 / Cyclin-dependent kinase 18 / Q07002*ENSMUSG0000002643760
Cdk14 / O35495 / Cyclin-dependent kinase 14 / O94921*ENSMUSG0000002892643
Cdk15 / Q3V3A1 / Cyclin-dependent kinase 15 / Q96Q40*ENSMUSG0000002602338


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006887 exocytosis IMP
 biological_processGO:0007283 spermatogenesis IMP
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030252 growth hormone secretion IMP
 biological_processGO:0031175 neuron projection development IMP
 biological_processGO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0008021 synaptic vesicle IDA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030133 transport vesicle IEA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001146 abnormal testis morphology "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6NCrj

 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
Show

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6NCrj

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6NCrj

 MP:0002208 abnormal germ cell morphology "anomalous structure of the germ cell, that is, any of the reproductive (generative) cells of a multicellular organism, whether they are undifferentiated or fully differentiated" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6NCrj

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6NCrj

 MP:0008892 abnormal sperm flagellum "any strucutral anomaly of the whiplike posterior filiform portion of the spermatozoon that provides sperm motility" [MESH:A05.360.490.890.840]
Show

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6NCrj

 MP:0009230 abnormal sperm head morphology "any structural abnormality of the head segment of the sperm cell which contains the nucleus with densely coiled chromatin fibers, and is surrounded anteriorly by the acrosome which contains enzymes used for penetrating the female egg" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6NCrj

 MP:0009834 abnormal sperm annulus morphology "any structural anomaly of the ring-like, filamentous structure located at the distal end of the midpiece of the sperm flagellum; the annulus is thought to form a diffusion barrier between the midpiece and the principal piece and serve as a stabilizing structure for tail rigidity" [PMID:14581499]
Show

Allelic Composition: Trp53tm1Tyj/Trp53tm1Tyj,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6NCrj

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr