ENSG00000060339


Homo sapiens

Features
Gene ID: ENSG00000060339
  
Biological name :CCAR1
  
Synonyms : CCAR1 / cell division cycle and apoptosis regulator 1 / Q8IX12
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q21.3
Gene start: 68721012
Gene end: 68792377
  
Corresponding Affymetrix probe sets: 224736_at (Human Genome U133 Plus 2.0 Array)   224737_x_at (Human Genome U133 Plus 2.0 Array)   239014_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000443808
Ensembl peptide - ENSP00000486408
Ensembl peptide - ENSP00000445254
Ensembl peptide - ENSP00000265872
Ensembl peptide - ENSP00000437760
Ensembl peptide - ENSP00000438610
Ensembl peptide - ENSP00000438881
Ensembl peptide - ENSP00000438939
Ensembl peptide - ENSP00000439153
Ensembl peptide - ENSP00000439252
Ensembl peptide - ENSP00000439571
Ensembl peptide - ENSP00000439642
Ensembl peptide - ENSP00000440224
Ensembl peptide - ENSP00000442410
NCBI entrez gene - 55749     See in Manteia.
OMIM - 612569
RefSeq - NM_001282960
RefSeq - NM_018237
RefSeq - NM_001282959
RefSeq Peptide - NP_001269888
RefSeq Peptide - NP_001269889
RefSeq Peptide - NP_060707
swissprot - F5H808
swissprot - H0YFJ7
swissprot - H0YFT7
swissprot - A0A0C4DGG8
swissprot - Q8IX12
swissprot - F5H1H2
swissprot - F5H1L3
swissprot - F5H2E6
swissprot - F5H3E1
swissprot - F5H3I8
swissprot - F5H7M9
Ensembl - ENSG00000060339
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ccar1ENSDARG00000074759Danio rerio
 CCAR1ENSGALG00000004108Gallus gallus
 Ccar1ENSMUSG00000020074Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CCAR2 / Q8N163 / cell cycle and apoptosis regulator 2ENSG0000015894128


Protein motifs (from Interpro)
Interpro ID Name
 IPR003034  SAP domain
 IPR011992  EF-hand domain pair
 IPR012340  Nucleic acid-binding, OB-fold
 IPR025223  S1-like RNA binding domain
 IPR025224  Cell cycle and apoptosis regulator protein
 IPR025954  DBC1/CARP1 catalytically inactive NUDIX hydrolase domain
 IPR036361  SAP domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0030335 positive regulation of cell migration IMP
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0001047 core promoter binding IDA
 molecular_functionGO:0003713 transcription coactivator activity IMP
 molecular_functionGO:0003714 transcription corepressor activity IMP
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity IGI


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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