ENSG00000065802


Homo sapiens

Features
Gene ID: ENSG00000065802
  
Biological name :ASB1
  
Synonyms : ankyrin repeat and SOCS box containing 1 / ASB1 / Q9Y576
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q37.3
Gene start: 238426742
Gene end: 238452250
  
Corresponding Affymetrix probe sets: 212818_s_at (Human Genome U133 Plus 2.0 Array)   212819_at (Human Genome U133 Plus 2.0 Array)   238991_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000411773
Ensembl peptide - ENSP00000264607
Ensembl peptide - ENSP00000387025
NCBI entrez gene - 51665     See in Manteia.
OMIM - 605758
RefSeq - XM_005246080
RefSeq - NM_001040445
RefSeq Peptide - NP_001035535
RefSeq Peptide - NP_001317125
swissprot - B9A047
swissprot - Q9Y576
swissprot - F8WBM8
Ensembl - ENSG00000065802
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 asb1ENSDARG00000026635Danio rerio
 ASB1ENSGALG00000004272Gallus gallus
 Asb1ENSMUSG00000026311Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASB12 / Q8WXK4 / ankyrin repeat and SOCS box containing 12ENSG0000019888135
ASB14 / A6NK59 / ankyrin repeat and SOCS box containing 14ENSG0000023938825
ASB2 / Q96Q27 / ankyrin repeat and SOCS box containing 2ENSG0000010062824
ASB5 / Q8WWX0 / ankyrin repeat and SOCS box containing 5ENSG0000016412224
ASB9 / Q96DX5 / ankyrin repeat and SOCS box containing 9ENSG0000010204824
ASB15 / Q8WXK1 / ankyrin repeat and SOCS box containing 15ENSG0000014680923
ASB13 / Q8WXK3 / ankyrin repeat and SOCS box containing 13ENSG0000019637222
ASB11 / Q8WXH4 / ankyrin repeat and SOCS box containing 11ENSG0000016519221
ASB3 / Q9Y575 / ankyrin repeat and SOCS box containing 3ENSG0000011523920
GPR75-ASB3 / GPR75-ASB3 readthroughENSG0000027089820
ASB7 / Q9H672 / ankyrin repeat and SOCS box containing 7ENSG0000018347519


Protein motifs (from Interpro)
Interpro ID Name
 IPR001496  SOCS box domain
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain
 IPR036036  SOCS box-like domain superfamily
 IPR036770  Ankyrin repeat-containing domain superfamily
 IPR037331  Ankyrin repeat and SOCS box protein 1, SOCS box domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030539 male genitalia development IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0042036 negative regulation of cytokine biosynthetic process NAS
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0000151 ubiquitin ligase complex IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0061630 ubiquitin protein ligase activity IDA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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