ENSMUSG00000026311


Mus musculus

Features
Gene ID: ENSMUSG00000026311
  
Biological name :Asb1
  
Synonyms : Ankyrin repeat and SOCS box protein 1 / Asb1 / Q9WV74
  
Possible biological names infered from orthology : ankyrin repeat and SOCS box containing 1 / Q9Y576
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: D
Gene start: 91540544
Gene end: 91559589
  
Corresponding Affymetrix probe sets: 10348618 (MoGene1.0st)   1430632_at (Mouse Genome 430 2.0 Array)   1434961_at (Mouse Genome 430 2.0 Array)   1436208_at (Mouse Genome 430 2.0 Array)   1444127_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000027538
Ensembl peptide - ENSMUSP00000140225
Ensembl peptide - ENSMUSP00000140731
Ensembl peptide - ENSMUSP00000140281
Ensembl peptide - ENSMUSP00000084054
Ensembl peptide - ENSMUSP00000140165
NCBI entrez gene - 65247     See in Manteia.
MGI - MGI:1929735
RefSeq - NM_023046
RefSeq - XM_006529790
RefSeq - XM_006529789
RefSeq - NM_001039126
RefSeq Peptide - NP_075533
RefSeq Peptide - NP_001034215
swissprot - A0A0A0MQ78
swissprot - Q3U5A0
swissprot - Q9WV74
swissprot - S4W2P0
swissprot - S4W6L8
swissprot - A0A087WQE9
swissprot - G3X9J5
Ensembl - ENSMUSG00000026311
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 asb1ENSDARG00000026635Danio rerio
 ASB1ENSGALG00000004272Gallus gallus
 ASB1ENSG00000065802Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Asb12 / Q9D738 / Ankyrin repeat and SOCS box protein 12 / Q8WXK4* / ankyrin repeat and SOCS box containing 12*ENSMUSG0000003120434
Asb2 / Q8K0L0 / Ankyrin repeat and SOCS box protein 2 / Q96Q27* / ankyrin repeat and SOCS box containing 2*ENSMUSG0000002120026
Asb14 / ankyrin repeat and SOCS box containing 14 / A6NK59*ENSMUSG0000002189826
Asb5 / Q9D1A4 / Ankyrin repeat and SOCS box protein 5 / Q8WWX0* / ankyrin repeat and SOCS box containing 5*ENSMUSG0000003151923
Asb9 / Q91ZT8 / Ankyrin repeat and SOCS box protein 9 / Q96DX5* / ankyrin repeat and SOCS box containing 9*ENSMUSG0000003138423
Asb15 / Q8VHS6 / Ankyrin repeat and SOCS box protein 15 / Q8WXK1* / ankyrin repeat and SOCS box containing 15*ENSMUSG0000002968522
Asb13 / Q8VBX0 / Ankyrin repeat and SOCS box protein 13 / Q8WXK3* / ankyrin repeat and SOCS box containing 13*ENSMUSG0000003378122
Asb11 / Q9CQ31 / Ankyrin repeat and SOCS box protein 11 / Q8WXH4* / ankyrin repeat and SOCS box containing 11*ENSMUSG0000003138221
Asb3 / Q9WV72 / Ankyrin repeat and SOCS box protein 3 / Q9Y575* / GPR75-ASB3* / GPR75-ASB3 readthrough* / ankyrin repeat and SOCS box containing 3*ENSMUSG0000002030521
Asb7 / Q91ZU0 / Ankyrin repeat and SOCS box protein 7 / Q9H672* / ankyrin repeat and SOCS box containing 7*ENSMUSG0000003050919


Protein motifs (from Interpro)
Interpro ID Name
 IPR001496  SOCS box domain
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain
 IPR036036  SOCS box-like domain superfamily
 IPR036770  Ankyrin repeat-containing domain superfamily
 IPR037331  Ankyrin repeat and SOCS box protein 1, SOCS box domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030539 male genitalia development IMP
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000692 small spleen "decreased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Fah2R/Fah2R
Genetic Background: BALB/cRl

 MP:0000694 spleen hypoplasia "small size due to reduced cell number in the spleen" [J:43971]
Show

Allelic Composition: Fah2R/Fah2R
Genetic Background: BALB/cRl

 MP:0001146 abnormal testis morphology "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Fah2R/Fah2R
Genetic Background: BALB/cRl

 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
Show

Allelic Composition: Fah2R/Fah2R
Genetic Background: BALB/cRl

 MP:0001219 thickened epidermis "increase in the width of the epidermal cell layer in the skin" [J:65146]
Show

Allelic Composition: Fah2R/Fah2R
Genetic Background: BALB/cRl

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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