ENSG00000066379


Homo sapiens

Features
Gene ID: ENSG00000066379
  
Biological name :ZNRD1
  
Synonyms : Q9P1U0 / zinc ribbon domain containing 1 / ZNRD1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p22.1
Gene start: 30058899
Gene end: 30064909
  
Corresponding Affymetrix probe sets: 223639_s_at (Human Genome U133 Plus 2.0 Array)   227673_at (Human Genome U133 Plus 2.0 Array)   228009_x_at (Human Genome U133 Plus 2.0 Array)   234114_at (Human Genome U133 Plus 2.0 Array)   234115_s_at (Human Genome U133 Plus 2.0 Array)   234530_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000331111
Ensembl peptide - ENSP00000352333
Ensembl peptide - ENSP00000365978
Ensembl peptide - ENSP00000365981
NCBI entrez gene - 30834     See in Manteia.
OMIM - 607525
RefSeq - NM_014596
RefSeq - NM_001278785
RefSeq - NM_001278786
RefSeq - NM_170783
RefSeq Peptide - NP_001265714
RefSeq Peptide - NP_001265715
RefSeq Peptide - NP_055411
RefSeq Peptide - NP_740753
swissprot - Q2L6J2
swissprot - Q9P1U0
Ensembl - ENSG00000066379
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 znrd1ENSDARG00000036070Danio rerio
 Znrd1ENSMUSG00000036315Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001222  Zinc finger, TFIIS-type
 IPR012164  DNA-directed RNA polymerase subunit/transcription factor S
 IPR019761  DNA-directed RNA polymerase M, 15kDa subunit, conserved site
 IPR034004  Pol I subunit A12, C-terminal zinc ribbon


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006139 nucleobase-containing compound metabolic process TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006361 transcription initiation from RNA polymerase I promoter TAS
 biological_processGO:0006362 transcription elongation from RNA polymerase I promoter TAS
 biological_processGO:0006363 termination of RNA polymerase I transcription IBA
 biological_processGO:0006379 mRNA cleavage IEA
 biological_processGO:0045815 positive regulation of gene expression, epigenetic TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005736 DNA-directed RNA polymerase I complex IBA
 molecular_functionGO:0001054 RNA polymerase I activity IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase I Chain Elongation
RNA Polymerase I Transcription Termination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr