ENSG00000066827


Homo sapiens

Features
Gene ID: ENSG00000066827
  
Biological name :ZFAT
  
Synonyms : Q9P243 / ZFAT / zinc finger and AT-hook domain containing
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q24.22
Gene start: 134477788
Gene end: 134713049
  
Corresponding Affymetrix probe sets: 226564_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000429050
Ensembl peptide - ENSP00000428483
Ensembl peptide - ENSP00000429091
Ensembl peptide - ENSP00000430924
Ensembl peptide - ENSP00000429983
Ensembl peptide - ENSP00000429930
Ensembl peptide - ENSP00000429600
Ensembl peptide - ENSP00000367069
Ensembl peptide - ENSP00000394501
Ensembl peptide - ENSP00000427831
Ensembl peptide - ENSP00000427879
Ensembl peptide - ENSP00000428192
NCBI entrez gene - 57623     See in Manteia.
OMIM - 610931
RefSeq - XM_017013716
RefSeq - NM_001029939
RefSeq - NM_001167583
RefSeq - NM_001174157
RefSeq - NM_001174158
RefSeq - NM_001289394
RefSeq - NM_020863
RefSeq - XM_011517203
RefSeq - XM_011517204
RefSeq - XM_011517206
RefSeq Peptide - NP_001276323
RefSeq Peptide - NP_065914
RefSeq Peptide - NP_001025110
RefSeq Peptide - NP_001161055
RefSeq Peptide - NP_001167628
RefSeq Peptide - NP_001167629
swissprot - E9PBN4
swissprot - E5RJT2
swissprot - E5RJL9
swissprot - E5RH37
swissprot - F8W7M8
swissprot - Q9P243
swissprot - E5RGN2
swissprot - H0YBJ1
swissprot - H0YC51
Ensembl - ENSG00000066827
  
Related genetic diseases (OMIM): 608175 - {Autoimmune thyroid disease, susceptibility to, 3}, 608175

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zfatENSDARG00000077987Danio rerio
 ZFATENSGALG00000037698Gallus gallus
 ZfatENSMUSG00000022335Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9H9D4 / ZNF408 / zinc finger protein 408ENSG0000017521313


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0030097 hemopoiesis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060712 spongiotrophoblast layer development IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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