ENSG00000068137


Homo sapiens

Features
Gene ID: ENSG00000068137
  
Biological name :PLEKHH3
  
Synonyms : pleckstrin homology, MyTH4 and FERM domain containing H3 / PLEKHH3 / Q7Z736
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q21.2
Gene start: 42667914
Gene end: 42676994
  
Corresponding Affymetrix probe sets: 220259_at (Human Genome U133 Plus 2.0 Array)   227248_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000293349
Ensembl peptide - ENSP00000465400
Ensembl peptide - ENSP00000467824
Ensembl peptide - ENSP00000468678
NCBI entrez gene - 79990     See in Manteia.
RefSeq - XM_017025118
RefSeq - NM_024927
RefSeq - XM_017025114
RefSeq - XM_017025115
RefSeq - XM_017025116
RefSeq - XM_017025117
RefSeq - XM_017025113
RefSeq Peptide - NP_079203
swissprot - Q7Z736
swissprot - X6R3U4
swissprot - K7EK04
Ensembl - ENSG00000068137
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-18i17.2ENSDARG00000070174Danio rerio
 PLEKHH3ENSGALG00000037269Gallus gallus
 Q8VCE9ENSMUSG00000035172Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8IVE3 / PLEKHH2 / pleckstrin homology, MyTH4 and FERM domain containing H2ENSG0000015252720
Q9ULM0 / PLEKHH1 / pleckstrin homology, MyTH4 and FERM domain containing H1ENSG0000005469019


Protein motifs (from Interpro)
Interpro ID Name
 IPR000159  Ras-associating (RA) domain
 IPR000299  FERM domain
 IPR000857  MyTH4 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR035963  FERM superfamily, second domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005856 cytoskeleton IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr