ENSG00000068383


Homo sapiens

Features
Gene ID: ENSG00000068383
  
Biological name :INPP5A
  
Synonyms : inositol polyphosphate-5-phosphatase A / INPP5A / Q14642
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q26.3
Gene start: 132537820
Gene end: 132783480
  
Corresponding Affymetrix probe sets: 1554757_a_at (Human Genome U133 Plus 2.0 Array)   203006_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000340707
Ensembl peptide - ENSP00000357583
Ensembl peptide - ENSP00000390749
Ensembl peptide - ENSP00000390936
Ensembl peptide - ENSP00000357582
NCBI entrez gene - 3632     See in Manteia.
OMIM - 600106
RefSeq - XM_017016205
RefSeq - NM_001321042
RefSeq - NM_005539
RefSeq - XM_017016204
RefSeq Peptide - NP_001307971
RefSeq Peptide - NP_005530
swissprot - Q14642
swissprot - Q5T1B3
swissprot - H0Y2W5
swissprot - Q5T1B5
swissprot - B1AP38
Ensembl - ENSG00000068383
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 inpp5lENSDARG00000053878Danio rerio
 INPP5AENSGALG00000010493Gallus gallus
 Inpp5aENSMUSG00000025477Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000300  Inositol polyphosphate-related phosphatase
 IPR005135  Endonuclease/exonuclease/phosphatase
 IPR036691  Endonuclease/exonuclease/phosphatase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043647 inositol phosphate metabolic process TAS
 biological_processGO:0046855 inositol phosphate dephosphorylation IBA
 biological_processGO:0046856 phosphatidylinositol dephosphorylation IEA
 biological_processGO:0048016 inositol phosphate-mediated signaling IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane NAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004445 inositol-polyphosphate 5-phosphatase activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042731 PH domain binding IPI
 molecular_functionGO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity IEA
 molecular_functionGO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of IP2, IP, and Ins in the cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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