ENSG00000068745


Homo sapiens

Features
Gene ID: ENSG00000068745
  
Biological name :IP6K2
  
Synonyms : inositol hexakisphosphate kinase 2 / IP6K2 / Q9UHH9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p21.31
Gene start: 48688003
Gene end: 48740353
  
Corresponding Affymetrix probe sets: 218192_at (Human Genome U133 Plus 2.0 Array)   223165_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000393797
Ensembl peptide - ENSP00000414428
Ensembl peptide - ENSP00000414139
Ensembl peptide - ENSP00000412121
Ensembl peptide - ENSP00000411776
Ensembl peptide - ENSP00000410950
Ensembl peptide - ENSP00000410454
Ensembl peptide - ENSP00000406357
Ensembl peptide - ENSP00000403968
Ensembl peptide - ENSP00000400812
Ensembl peptide - ENSP00000399052
Ensembl peptide - ENSP00000396904
Ensembl peptide - ENSP00000396203
Ensembl peptide - ENSP00000395819
Ensembl peptide - ENSP00000394488
Ensembl peptide - ENSP00000331103
Ensembl peptide - ENSP00000341925
Ensembl peptide - ENSP00000387394
Ensembl peptide - ENSP00000387759
Ensembl peptide - ENSP00000388116
Ensembl peptide - ENSP00000388420
Ensembl peptide - ENSP00000389755
Ensembl peptide - ENSP00000389761
Ensembl peptide - ENSP00000393077
NCBI entrez gene - 51447     See in Manteia.
OMIM - 606992
RefSeq - XM_017006593
RefSeq - NM_001146179
RefSeq - NM_001190316
RefSeq - NM_001190317
RefSeq - NM_016291
RefSeq - XM_006713199
RefSeq - XM_006713200
RefSeq - XM_006713201
RefSeq - XM_006713202
RefSeq - XM_011533816
RefSeq - XM_011533817
RefSeq - XM_011533818
RefSeq - XM_011533822
RefSeq - XM_011533823
RefSeq - XM_017006583
RefSeq - XM_017006584
RefSeq - XM_017006585
RefSeq - XM_017006586
RefSeq - XM_017006587
RefSeq - XM_017006588
RefSeq - XM_017006589
RefSeq - XM_017006590
RefSeq - XM_017006591
RefSeq - XM_017006592
RefSeq - NM_001005909
RefSeq - NM_001005910
RefSeq - NM_001005911
RefSeq - NM_001146178
RefSeq Peptide - NP_001139651
RefSeq Peptide - NP_001177245
RefSeq Peptide - NP_001177246
RefSeq Peptide - NP_057375
RefSeq Peptide - NP_001005911
RefSeq Peptide - NP_001139650
RefSeq Peptide - NP_001005909
RefSeq Peptide - NP_001005910
swissprot - C9J3W9
swissprot - C9J124
swissprot - B2RCP4
swissprot - C9JMC9
swissprot - F8WDQ5
swissprot - Q9UHH9
swissprot - C9JU99
swissprot - C9JRM0
swissprot - C9JLG7
swissprot - C9JHX0
swissprot - C9JHV2
swissprot - C9JGK2
swissprot - C9J8W6
swissprot - C9J790
swissprot - C9J536
Ensembl - ENSG00000068745
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ip6k2aENSDARG00000008310Danio rerio
 ip6k2bENSDARG00000019613Danio rerio
 IP6K2ENSGALG00000005701Gallus gallus
 Ip6k2ENSMUSG00000032599Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IP6K1 / Q92551 / inositol hexakisphosphate kinase 1ENSG0000017609547
IP6K3 / Q96PC2 / inositol hexakisphosphate kinase 3ENSG0000016189643
IPMK / Q8NFU5 / inositol polyphosphate multikinaseENSG0000015115123


Protein motifs (from Interpro)
Interpro ID Name
 IPR005522  Inositol polyphosphate kinase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006817 phosphate ion transport IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030308 negative regulation of cell growth IMP
 biological_processGO:0032958 inositol phosphate biosynthetic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process IMP
 biological_processGO:0043647 inositol phosphate metabolic process TAS
 biological_processGO:0046854 phosphatidylinositol phosphorylation IDA
 biological_processGO:0060337 type I interferon signaling pathway TAS
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0030054 cell junction IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000827 inositol-1,3,4,5,6-pentakisphosphate kinase activity TAS
 molecular_functionGO:0000828 inositol hexakisphosphate kinase activity IDA
 molecular_functionGO:0000829 inositol heptakisphosphate kinase activity TAS
 molecular_functionGO:0000832 inositol hexakisphosphate 5-kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0052723 inositol hexakisphosphate 1-kinase activity IEA
 molecular_functionGO:0052724 inositol hexakisphosphate 3-kinase activity IEA
 molecular_functionGO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity TAS
 molecular_functionGO:0052839 inositol diphosphate tetrakisphosphate kinase activity TAS


Pathways (from Reactome)
Pathway description
Synthesis of IPs in the nucleus
Interferon alpha/beta signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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