ENSG00000070190


Homo sapiens

Features
Gene ID: ENSG00000070190
  
Biological name :DAPP1
  
Synonyms : DAPP1 / dual adaptor of phosphotyrosine and 3-phosphoinositides 1 / Q9UN19
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q23
Gene start: 99816833
Gene end: 99870154
  
Corresponding Affymetrix probe sets: 219290_x_at (Human Genome U133 Plus 2.0 Array)   222858_s_at (Human Genome U133 Plus 2.0 Array)   222859_s_at (Human Genome U133 Plus 2.0 Array)   236707_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000296414
Ensembl peptide - ENSP00000423602
NCBI entrez gene - 27071     See in Manteia.
OMIM - 605768
RefSeq - XM_017008024
RefSeq - NM_001306151
RefSeq - NM_014395
RefSeq - XM_011531840
RefSeq - XM_011531842
RefSeq - XM_011531843
RefSeq - XM_017008023
RefSeq Peptide - NP_001293080
RefSeq Peptide - NP_055210
swissprot - Q9UN19
swissprot - J3KNB3
Ensembl - ENSG00000070190
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dapp1ENSDARG00000039535Danio rerio
 DAPP1ENSGALG00000043681Gallus gallus
 Dapp1ENSMUSG00000028159Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR035843  DAPP1, SH2 domain
 IPR036860  SH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation NAS
 biological_processGO:0007165 signal transduction TAS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005543 phospholipid binding NAS
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IDA
 molecular_functionGO:0030165 PDZ domain binding IBA
 molecular_functionGO:0043325 phosphatidylinositol-3,4-bisphosphate binding IDA


Pathways (from Reactome)
Pathway description
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000197943 PLCG2 / P16885 / phospholipase C gamma 2  / reaction / complex






 

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