ENSG00000071127


Homo sapiens

Features
Gene ID: ENSG00000071127
  
Biological name :WDR1
  
Synonyms : O75083 / WDR1 / WD repeat domain 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: p16.1
Gene start: 10074339
Gene end: 10116949
  
Corresponding Affymetrix probe sets: 200609_s_at (Human Genome U133 Plus 2.0 Array)   200611_s_at (Human Genome U133 Plus 2.0 Array)   210935_s_at (Human Genome U133 Plus 2.0 Array)   210936_at (Human Genome U133 Plus 2.0 Array)   240282_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000426725
Ensembl peptide - ENSP00000427687
Ensembl peptide - ENSP00000371889
Ensembl peptide - ENSP00000371890
Ensembl peptide - ENSP00000425481
NCBI entrez gene - 9948     See in Manteia.
OMIM - 604734
RefSeq - NM_005112
RefSeq - XM_017008880
RefSeq - NM_017491
RefSeq Peptide - NP_059830
RefSeq Peptide - NP_005103
swissprot - O75083
swissprot - V9HWG7
swissprot - D6RD66
Ensembl - ENSG00000071127
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 WDR1ENSDARG00000114022Danio rerio
 WDR1ENSGALG00000014957Gallus gallus
 Wdr1ENSMUSG00000005103Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR011045  Nitrous oxide reductase, N-terminal
 IPR011047  Quinoprotein alcohol dehydrogenase-like superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002446 neutrophil mediated immunity IEA
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0007605 sensory perception of sound TAS
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0030043 actin filament fragmentation IEA
 biological_processGO:0030220 platelet formation IEA
 biological_processGO:0030834 regulation of actin filament depolymerization IDA
 biological_processGO:0030836 positive regulation of actin filament depolymerization IBA
 biological_processGO:0030865 cortical cytoskeleton organization IEA
 biological_processGO:0040011 locomotion IBA
 biological_processGO:0042247 establishment of planar polarity of follicular epithelium IEA
 biological_processGO:0043297 apical junction assembly IDA
 biological_processGO:0045199 maintenance of epithelial cell apical/basal polarity IDA
 biological_processGO:0045214 sarcomere organization IBA
 biological_processGO:0048713 regulation of oligodendrocyte differentiation IEA
 biological_processGO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization IEA
 biological_processGO:1990266 neutrophil migration IEA
 cellular_componentGO:0002102 podosome IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005884 actin filament IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030864 cortical actin cytoskeleton IBA
 cellular_componentGO:0042643 actomyosin, actin portion IBA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0051015 actin filament binding IBA


Pathways (from Reactome)
Pathway description
Platelet degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr