ENSG00000078053


Homo sapiens

Features
Gene ID: ENSG00000078053
  
Biological name :AMPH
  
Synonyms : AMPH / amphiphysin / P49418
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p14.1
Gene start: 38383704
Gene end: 38631567
  
Corresponding Affymetrix probe sets: 205257_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000317441
Ensembl peptide - ENSP00000348602
Ensembl peptide - ENSP00000400404
Ensembl peptide - ENSP00000415085
NCBI entrez gene - 273     See in Manteia.
OMIM - 600418
RefSeq - XM_017011996
RefSeq - XM_006715689
RefSeq - XM_006715690
RefSeq - XM_006715691
RefSeq - XM_011515271
RefSeq - XM_017011995
RefSeq - NM_001635
RefSeq - NM_139316
RefSeq Peptide - NP_001626
RefSeq Peptide - NP_647477
swissprot - H0Y7T8
swissprot - P49418
swissprot - H0Y5S4
Ensembl - ENSG00000078053
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 amphENSDARG00000007663Danio rerio
 AMPHENSGALG00000032958Gallus gallus
 AmphENSMUSG00000021314Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BIN1 / O00499 / bridging integrator 1ENSG0000013671741
BIN2 / bridging integrator 2ENSG0000011093424


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR003005  Amphiphysin
 IPR003017  Amphiphysin, isoform 1
 IPR004148  BAR domain
 IPR027267  AH/BAR domain superfamily
 IPR035470  Amphiphysin I, SH3 domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis TAS
 biological_processGO:0007268 chemical synaptic transmission TAS
 biological_processGO:0061024 membrane organization TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0008021 synaptic vesicle TAS
 cellular_componentGO:0015629 actin cytoskeleton TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030672 synaptic vesicle membrane IEA
 cellular_componentGO:0031256 leading edge membrane IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005543 phospholipid binding IDA


Pathways (from Reactome)
Pathway description
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000136717 BIN1 / O00499 / bridging integrator 1  / complex






 

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