ENSG00000078124


Homo sapiens

Features
Gene ID: ENSG00000078124
  
Biological name :ACER3
  
Synonyms : ACER3 / alkaline ceramidase 3 / Q9NUN7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.5
Gene start: 76860867
Gene end: 77026797
  
Corresponding Affymetrix probe sets: 222687_s_at (Human Genome U133 Plus 2.0 Array)   222688_at (Human Genome U133 Plus 2.0 Array)   222689_at (Human Genome U133 Plus 2.0 Array)   227776_at (Human Genome U133 Plus 2.0 Array)   231321_s_at (Human Genome U133 Plus 2.0 Array)   238945_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000431149
Ensembl peptide - ENSP00000436252
Ensembl peptide - ENSP00000435733
Ensembl peptide - ENSP00000435048
Ensembl peptide - ENSP00000434480
Ensembl peptide - ENSP00000433368
Ensembl peptide - ENSP00000432379
Ensembl peptide - ENSP00000432109
Ensembl peptide - ENSP00000431504
Ensembl peptide - ENSP00000278544
NCBI entrez gene - 55331     See in Manteia.
OMIM - 617036
RefSeq - XM_017017988
RefSeq - NM_001300953
RefSeq - NM_001300954
RefSeq - NM_001300955
RefSeq - NM_018367
RefSeq - XM_011545151
RefSeq - XM_011545152
RefSeq - XM_011545153
RefSeq Peptide - NP_060837
RefSeq Peptide - NP_001287882
RefSeq Peptide - NP_001287883
RefSeq Peptide - NP_001287884
swissprot - E9PKR3
swissprot - E9PIN9
swissprot - B7Z2V2
swissprot - B7Z2Q2
swissprot - E9PLZ9
swissprot - J3KN85
swissprot - Q9NUN7
swissprot - E9PR08
swissprot - E9PL35
Ensembl - ENSG00000078124
  
Related genetic diseases (OMIM): 617762 - ?Leukodystrophy, progressive, early childhood-onset, 617762
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acer3ENSDARG00000093366Danio rerio
 ACER3ENSGALG00000000755Gallus gallus
 Acer3ENSMUSG00000030760Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008901  Ceramidase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006672 ceramide metabolic process IEA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0030148 sphingolipid biosynthetic process TAS
 biological_processGO:0046512 sphingosine biosynthetic process IDA
 biological_processGO:0071602 phytosphingosine biosynthetic process IDA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030173 integral component of Golgi membrane IDA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides IEA
 molecular_functionGO:0070774 phytoceramidase activity TAS


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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