ENSG00000081177


Homo sapiens

Features
Gene ID: ENSG00000081177
  
Biological name :EXD2
  
Synonyms : EXD2 / exonuclease 3-5 domain containing 2 / Q9NVH0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q24.1
Gene start: 69191511
Gene end: 69244020
  
Corresponding Affymetrix probe sets: 1555808_a_at (Human Genome U133 Plus 2.0 Array)   218363_at (Human Genome U133 Plus 2.0 Array)   229131_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000387331
Ensembl peptide - ENSP00000386915
Ensembl peptide - ENSP00000409089
Ensembl peptide - ENSP00000313140
Ensembl peptide - ENSP00000386632
Ensembl peptide - ENSP00000386762
Ensembl peptide - ENSP00000386839
NCBI entrez gene - 55218     See in Manteia.
OMIM - 616940
RefSeq - XM_017021421
RefSeq - NM_001193360
RefSeq - NM_001193361
RefSeq - NM_001193362
RefSeq - NM_001193363
RefSeq - NM_018199
RefSeq - XM_005267817
RefSeq - XM_011536908
RefSeq Peptide - NP_001180289
RefSeq Peptide - NP_001180290
RefSeq Peptide - NP_060669
RefSeq Peptide - NP_001180291
RefSeq Peptide - NP_001180292
swissprot - Q9NVH0
swissprot - C9JLF4
Ensembl - ENSG00000081177
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 exd2ENSDARG00000016117Danio rerio
 EXD2ENSGALG00000009456Gallus gallus
 Exd2ENSMUSG00000032705Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002562  3"-5" exonuclease domain
 IPR012337  Ribonuclease H-like superfamily
 IPR036397  Ribonuclease H superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000724 double-strand break repair via homologous recombination IDA
 biological_processGO:0000729 DNA double-strand break processing IDA
 biological_processGO:0006139 nucleobase-containing compound metabolic process IEA
 biological_processGO:0006302 double-strand break repair IDA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IDA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008310 single-stranded DNA 3"-5" exodeoxyribonuclease activity IDA
 molecular_functionGO:0008408 3"-5" exonuclease activity IDA
 molecular_functionGO:0008852 exodeoxyribonuclease I activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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