ENSG00000082014


Homo sapiens

Features
Gene ID: ENSG00000082014
  
Biological name :SMARCD3
  
Synonyms : Q6STE5 / SMARCD3 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q36.1
Gene start: 151238764
Gene end: 151277896
  
Corresponding Affymetrix probe sets: 204099_at (Human Genome U133 Plus 2.0 Array)   231144_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417145
Ensembl peptide - ENSP00000376558
Ensembl peptide - ENSP00000417908
Ensembl peptide - ENSP00000419886
Ensembl peptide - ENSP00000262188
Ensembl peptide - ENSP00000349254
NCBI entrez gene - 6604     See in Manteia.
OMIM - 601737
RefSeq - XM_017012556
RefSeq - NM_001003801
RefSeq - NM_001003802
RefSeq - NM_003078
RefSeq - XM_011516521
RefSeq Peptide - NP_001003802
RefSeq Peptide - NP_001003801
RefSeq Peptide - NP_003069
swissprot - F8WBJ3
swissprot - H7C4E9
swissprot - C9JYI7
swissprot - A0A090N8Z9
swissprot - Q6STE5
Ensembl - ENSG00000082014
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smarcd3aENSDARG00000038786Danio rerio
 smarcd3bENSDARG00000019969Danio rerio
 SMARCD3ENSGALG00000043137Gallus gallus
 Q6P9Z1ENSMUSG00000028949Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96GM5 / SMARCD1 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1ENSG0000006611772
Q92925 / SMARCD2 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2ENSG0000010860467


Protein motifs (from Interpro)
Interpro ID Name
 IPR003121  SWIB/MDM2 domain
 IPR019835  SWIB domain
 IPR036885  SWIB/MDM2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002052 positive regulation of neuroblast proliferation IDA
 biological_processGO:0003007 heart morphogenesis IEA
 biological_processGO:0003139 secondary heart field specification IEA
 biological_processGO:0003219 cardiac right ventricle formation IEA
 biological_processGO:0003407 neural retina development IEP
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006337 nucleosome disassembly IDA
 biological_processGO:0006338 chromatin remodeling IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II NAS
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0010971 positive regulation of G2/M transition of mitotic cell cycle IEA
 biological_processGO:0019216 regulation of lipid metabolic process TAS
 biological_processGO:0042692 muscle cell differentiation IEA
 biological_processGO:0043393 regulation of protein binding IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0051152 positive regulation of smooth muscle cell differentiation IEA
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0016514 SWI/SNF complex IDA
 cellular_componentGO:0071564 npBAF complex IDA
 cellular_componentGO:0071565 nBAF complex ISS
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003713 transcription coactivator activity NAS
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0035257 nuclear hormone receptor binding IPI


Pathways (from Reactome)
Pathway description
RORA activates gene expression
BMAL1:CLOCK,NPAS2 activates circadian gene expression
PPARA activates gene expression
Transcriptional activation of mitochondrial biogenesis
Activation of gene expression by SREBF (SREBP)
RMTs methylate histone arginines
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Circadian Clock
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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