ENSG00000085377


Homo sapiens

Features
Gene ID: ENSG00000085377
  
Biological name :PREP
  
Synonyms : P48147 / PREP / prolyl endopeptidase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: q21
Gene start: 105277565
Gene end: 105403084
  
Corresponding Affymetrix probe sets: 204117_at (Human Genome U133 Plus 2.0 Array)   229644_at (Human Genome U133 Plus 2.0 Array)   37950_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358106
Ensembl peptide - ENSP00000401796
NCBI entrez gene - 5550     See in Manteia.
OMIM - 600400
RefSeq - XM_011535925
RefSeq - NM_002726
RefSeq - XM_005267044
RefSeq Peptide - NP_002717
swissprot - P48147
swissprot - H0Y5Y0
Ensembl - ENSG00000085377
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prepENSDARG00000057151Danio rerio
 PREPENSGALG00000015405Gallus gallus
 PrepENSMUSG00000019849Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PREPL / Q4J6C6 / prolyl endopeptidase likeENSG0000013807818


Protein motifs (from Interpro)
Interpro ID Name
 IPR001375  Peptidase S9, prolyl oligopeptidase, catalytic domain
 IPR002470  Peptidase S9A, prolyl oligopeptidase
 IPR002471  Peptidase S9, serine active site
 IPR023302  Peptidase S9A, N-terminal domain
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane HDA
 molecular_functionGO:0004252 serine-type endopeptidase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0070008 serine-type exopeptidase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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