ENSG00000085760


Homo sapiens

Features
Gene ID: ENSG00000085760
  
Biological name :MTIF2
  
Synonyms : mitochondrial translational initiation factor 2 / MTIF2 / P46199
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p16.1
Gene start: 55236595
Gene end: 55269347
  
Corresponding Affymetrix probe sets: 203095_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000388640
Ensembl peptide - ENSP00000384481
Ensembl peptide - ENSP00000393025
Ensembl peptide - ENSP00000416057
Ensembl peptide - ENSP00000403492
Ensembl peptide - ENSP00000399531
Ensembl peptide - ENSP00000393337
Ensembl peptide - ENSP00000263629
Ensembl peptide - ENSP00000378099
Ensembl peptide - ENSP00000383880
NCBI entrez gene - 4528     See in Manteia.
OMIM - 603766
RefSeq - XM_017004167
RefSeq - NM_001005369
RefSeq - NM_001321001
RefSeq - NM_001321002
RefSeq - NM_001321003
RefSeq - NM_001321004
RefSeq - NM_001321005
RefSeq - NM_002453
RefSeq - XM_005264335
RefSeq - XM_011532871
RefSeq - XM_017004162
RefSeq - XM_017004163
RefSeq - XM_017004164
RefSeq - XM_017004165
RefSeq - XM_017004166
RefSeq Peptide - NP_001307930
RefSeq Peptide - NP_001307931
RefSeq Peptide - NP_001307932
RefSeq Peptide - NP_001307933
RefSeq Peptide - NP_001307934
RefSeq Peptide - NP_002444
RefSeq Peptide - NP_001005369
swissprot - P46199
swissprot - C9JIY5
swissprot - B5MCU1
swissprot - A0A1Y8EJN7
swissprot - H7C213
swissprot - A0A1D5RMP2
swissprot - E7EW07
Ensembl - ENSG00000085760
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mtif2ENSDARG00000063213Danio rerio
 MTIF2ENSGALG00000031265Gallus gallus
 Mtif2ENSMUSG00000020459Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000178  Translation initiation factor aIF-2, bacterial-like
 IPR000795  Transcription factor, GTP-binding domain
 IPR005225  Small GTP-binding protein domain
 IPR009000  Translation protein, beta-barrel domain superfamily
 IPR015760  Translation initiation factor IF- 2
 IPR023115  Translation initiation factor IF- 2, domain 3
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036925  Translation initiation factor IF-2, domain 3 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0006446 regulation of translational initiation TAS
 biological_processGO:0032790 ribosome disassembly ISS
 biological_processGO:0070124 mitochondrial translational initiation ISS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005739 mitochondrion TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003743 translation initiation factor activity IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0008135 translation factor activity, RNA binding ISS
 molecular_functionGO:0043024 ribosomal small subunit binding ISS


Pathways (from Reactome)
Pathway description
Mitochondrial translation initiation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000122033 MTIF3 / Q9H2K0 / mitochondrial translational initiation factor 3  / reaction






 

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