ENSG00000088205


Homo sapiens

Features
Gene ID: ENSG00000088205
  
Biological name :DDX18
  
Synonyms : DDX18 / DEAD-box helicase 18 / Q9NVP1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q14.1
Gene start: 117814650
Gene end: 117832379
  
Corresponding Affymetrix probe sets: 205763_s_at (Human Genome U133 Plus 2.0 Array)   208895_s_at (Human Genome U133 Plus 2.0 Array)   208896_at (Human Genome U133 Plus 2.0 Array)   208897_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000263239
Ensembl peptide - ENSP00000415604
NCBI entrez gene - 8886     See in Manteia.
OMIM - 606355
RefSeq - NM_006773
RefSeq Peptide - NP_006764
swissprot - A0A024RAH8
swissprot - H7C452
swissprot - Q9NVP1
Ensembl - ENSG00000088205
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddx18ENSDARG00000030789Danio rerio
 DDX18ENSGALG00000012147Gallus gallus
 Ddx18ENSMUSG00000001674Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR025313  Domain of unknown function DUF4217
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 biological_processGO:0071392 cellular response to estradiol stimulus IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016020 membrane HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity TAS
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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