ENSG00000088766


Homo sapiens

Features
Gene ID: ENSG00000088766
  
Biological name :CRLS1
  
Synonyms : cardiolipin synthase 1 / CRLS1 / Q9UJA2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: p12.3
Gene start: 6006090
Gene end: 6040053
  
Corresponding Affymetrix probe sets: 223978_s_at (Human Genome U133 Plus 2.0 Array)   225324_at (Human Genome U133 Plus 2.0 Array)   226937_at (Human Genome U133 Plus 2.0 Array)   237502_at (Human Genome U133 Plus 2.0 Array)   241741_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000368145
Ensembl peptide - ENSP00000416770
Ensembl peptide - ENSP00000368140
NCBI entrez gene - 54675     See in Manteia.
OMIM - 608188
RefSeq - NM_001323564
RefSeq - NM_019095
RefSeq - XM_005260738
RefSeq - NM_001127458
RefSeq - NM_001323561
RefSeq - NM_001323562
RefSeq - NM_001323563
RefSeq Peptide - NP_001120930
RefSeq Peptide - NP_001310491
RefSeq Peptide - NP_001310492
RefSeq Peptide - NP_001310493
RefSeq Peptide - NP_061968
RefSeq Peptide - NP_001310490
swissprot - Q9UJA2
swissprot - Q6NTG3
Ensembl - ENSG00000088766
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crls1ENSDARG00000038000Danio rerio
 CRLS1ENSGALG00000009214Gallus gallus
 Crls1ENSMUSG00000027357Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000462  CDP-alcohol phosphatidyltransferase
 IPR004570  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0008654 phospholipid biosynthetic process IEA
 biological_processGO:0032049 cardiolipin biosynthetic process TAS
 biological_processGO:0036148 phosphatidylglycerol acyl-chain remodeling TAS
 biological_processGO:0097068 response to thyroxine IEA
 biological_processGO:1905711 response to phosphatidylethanolamine IEA
 cellular_componentGO:0005739 mitochondrion IBA
 cellular_componentGO:0005743 mitochondrial inner membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 molecular_functionGO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity TAS
 molecular_functionGO:0008444 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity IEA
 molecular_functionGO:0008808 cardiolipin synthase activity IBA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016780 phosphotransferase activity, for other substituted phosphate groups IEA
 molecular_functionGO:0043337 CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity TAS
 molecular_functionGO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity TAS


Pathways (from Reactome)
Pathway description
Acyl chain remodelling of PG
Synthesis of CL


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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