ENSMUSG00000027357


Mus musculus

Features
Gene ID: ENSMUSG00000027357
  
Biological name :Crls1
  
Synonyms : Cardiolipin synthase (CMP-forming) / Crls1 / Q80ZM8
  
Possible biological names infered from orthology : cardiolipin synthase 1 / Q9UJA2
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: F2
Gene start: 132846666
Gene end: 132866785
  
Corresponding Affymetrix probe sets: 10476383 (MoGene1.0st)   1429737_a_at (Mouse Genome 430 2.0 Array)   1431930_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028835
Ensembl peptide - ENSMUSP00000132682
Ensembl peptide - ENSMUSP00000129509
Ensembl peptide - ENSMUSP00000129137
Ensembl peptide - ENSMUSP00000105749
NCBI entrez gene - 66586     See in Manteia.
MGI - MGI:1913836
RefSeq - XM_006500012
RefSeq - NM_001024385
RefSeq - NM_025646
RefSeq Peptide - NP_001019556
RefSeq Peptide - NP_079922
swissprot - E9PYF8
swissprot - E9PUW6
swissprot - A0A0C3SFZ5
swissprot - E9PUH6
swissprot - Q80ZM8
Ensembl - ENSMUSG00000027357
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crls1ENSDARG00000038000Danio rerio
 CRLS1ENSGALG00000009214Gallus gallus
 CRLS1ENSG00000088766Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000462  CDP-alcohol phosphatidyltransferase
 IPR004570  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0008654 phospholipid biosynthetic process IEA
 biological_processGO:0032049 cardiolipin biosynthetic process IBA
 biological_processGO:0097068 response to thyroxine IEA
 biological_processGO:1905711 response to phosphatidylethanolamine IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 molecular_functionGO:0008444 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity IEA
 molecular_functionGO:0008808 cardiolipin synthase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016780 phosphotransferase activity, for other substituted phosphate groups IEA


Pathways (from Reactome)
Pathway description
Acyl chain remodelling of PG
Synthesis of CL


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005014 increased B cell number "greater than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

 MP:0008210 increased mature B cell number "greater number of the mature form of B cells, a type of lymphocyte whose defining characteristic is the expression of an immunoglobulin complex" [CL:0000785, ISBN:0781735149]
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Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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