ENSG00000090539


Homo sapiens

Features
Gene ID: ENSG00000090539
  
Biological name :CHRD
  
Synonyms : chordin / CHRD / Q9H2X0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q27.1
Gene start: 184380073
Gene end: 184390736
  
Corresponding Affymetrix probe sets: 211248_s_at (Human Genome U133 Plus 2.0 Array)   221674_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000408624
Ensembl peptide - ENSP00000392794
Ensembl peptide - ENSP00000408972
Ensembl peptide - ENSP00000204604
Ensembl peptide - ENSP00000334036
Ensembl peptide - ENSP00000348930
NCBI entrez gene - 8646     See in Manteia.
OMIM - 603475
RefSeq - XM_017007394
RefSeq - NM_001304472
RefSeq - NM_001304473
RefSeq - NM_001304474
RefSeq - NM_003741
RefSeq - XM_017007388
RefSeq - XM_017007389
RefSeq - XM_017007390
RefSeq - XM_017007391
RefSeq - XM_017007392
RefSeq - XM_017007393
RefSeq - XM_011513254
RefSeq - XM_011513256
RefSeq Peptide - NP_001291401
RefSeq Peptide - NP_001291402
RefSeq Peptide - NP_001291403
RefSeq Peptide - NP_003732
swissprot - Q9H2X0
swissprot - E7ESX1
Ensembl - ENSG00000090539
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chrdENSDARG00000006110Danio rerio
 CHRDENSGALG00000026983Gallus gallus
 ChrdENSMUSG00000006958Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CHRDL2 / Q6WN34 / chordin like 2ENSG0000005493811
CHRDL1 / Q9BU40 / chordin like 1ENSG0000010193810


Protein motifs (from Interpro)
Interpro ID Name
 IPR001007  VWFC domain
 IPR010895  CHRD
 IPR016353  Chordin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development TAS
 biological_processGO:0001649 osteoblast differentiation IEA
 biological_processGO:0001702 gastrulation with mouth forming second IEA
 biological_processGO:0001707 mesoderm formation IEA
 biological_processGO:0002053 positive regulation of mesenchymal cell proliferation IMP
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007389 pattern specification process IEA
 biological_processGO:0007417 central nervous system development IEA
 biological_processGO:0009953 dorsal/ventral pattern formation IEA
 biological_processGO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning IMP
 biological_processGO:0030336 negative regulation of cell migration IDA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IMP
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0033504 floor plate development TAS
 biological_processGO:0045668 negative regulation of osteoblast differentiation IMP
 biological_processGO:0045785 positive regulation of cell adhesion IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0019955 cytokine binding NAS
 molecular_functionGO:0045545 syndecan binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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