ENSG00000090612


Homo sapiens

Features
Gene ID: ENSG00000090612
  
Biological name :ZNF268
  
Synonyms : Q14587 / zinc finger protein 268 / ZNF268
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q24.33
Gene start: 133181409
Gene end: 133214831
  
Corresponding Affymetrix probe sets: 209989_at (Human Genome U133 Plus 2.0 Array)   238030_at (Human Genome U133 Plus 2.0 Array)   238192_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000466629
Ensembl peptide - ENSP00000466622
Ensembl peptide - ENSP00000467781
Ensembl peptide - ENSP00000479191
Ensembl peptide - ENSP00000467922
Ensembl peptide - ENSP00000228289
Ensembl peptide - ENSP00000409295
Ensembl peptide - ENSP00000437410
Ensembl peptide - ENSP00000437858
Ensembl peptide - ENSP00000438941
Ensembl peptide - ENSP00000439539
Ensembl peptide - ENSP00000442446
Ensembl peptide - ENSP00000443721
Ensembl peptide - ENSP00000444412
Ensembl peptide - ENSP00000446153
Ensembl peptide - ENSP00000464721
NCBI entrez gene - 10795     See in Manteia.
OMIM - 604753
RefSeq - NM_001165881
RefSeq - NM_001165882
RefSeq - NM_001165883
RefSeq - NM_001165884
RefSeq - NM_001165885
RefSeq - NM_001165886
RefSeq - NM_001165887
RefSeq - NM_003415
RefSeq - NM_152943
RefSeq Peptide - NP_001159354
RefSeq Peptide - NP_001159356
RefSeq Peptide - NP_001159357
RefSeq Peptide - NP_001159358
RefSeq Peptide - NP_001159359
RefSeq Peptide - NP_003406
RefSeq Peptide - NP_694422
RefSeq Peptide - NP_001159355
RefSeq Peptide - NP_001159353
swissprot - F5H670
swissprot - F5H6R9
swissprot - F5H7L3
swissprot - K7EIF0
swissprot - F5H848
swissprot - K7EMS6
swissprot - K7EQP6
swissprot - A0A075B6T9
swissprot - Q14587
swissprot - E7EV44
swissprot - A0A087WV54
swissprot - F5H1T2
swissprot - F5H467
Ensembl - ENSG00000090612
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkeyp-82h4.3ENSDARG00000102062Danio rerio
 znf1021ENSDARG00000114646Danio rerio
 znf1026ENSDARG00000114894Danio rerio
 znf976ENSDARG00000113626Danio rerio
 znf985ENSDARG00000114783Danio rerio
 znf985ENSDARG00000109604Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A8MQ14 / ZNF850 / zinc finger protein 850ENSG0000026704146
Q6P3V2 / ZNF585A / zinc finger protein 585AENSG0000019696744
Q52M93 / ZNF585B / zinc finger protein 585BENSG0000024568043
Q9P2J8 / ZNF624 / zinc finger protein 624ENSG0000019756642
Q5TYW1 / ZNF658 / zinc finger protein 658ENSG0000027434941
ZFP62 / Q8NB50 / ZFP62 zinc finger proteinENSG0000019667041
Q6ZN19 / ZNF841 / zinc finger protein 841ENSG0000019760840
A6NN14 / ZNF729 / zinc finger protein 729ENSG0000019635040
O14709 / ZNF197 / zinc finger protein 197ENSG0000018644840
Q96IR2 / ZNF845 / zinc finger protein 845ENSG0000021379939
Q9HCG1 / ZNF160 / zinc finger protein 160ENSG0000017094939
Q96SE7 / ZNF347 / zinc finger protein 347ENSG0000019793739
Q96JF6 / ZNF594 / zinc finger protein 594ENSG0000018062639
Q8TF20 / ZNF721 / zinc finger protein 721ENSG0000018290336
ZNF99 / A8MXY4 / zinc finger protein 99ENSG0000021397334
Q9H0M5 / ZNF700 / zinc finger protein 700ENSG0000019675733


Protein motifs (from Interpro)
Interpro ID Name
 IPR001909  Krueppel-associated box
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036051  KRAB domain superfamily
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IMP
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030335 positive regulation of cell migration IMP
 biological_processGO:0043065 positive regulation of apoptotic process IMP
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0045597 positive regulation of cell differentiation IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0071157 negative regulation of cell cycle arrest IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus NAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding NAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Generic Transcription Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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