ENSG00000090989


Homo sapiens

Features
Gene ID: ENSG00000090989
  
Biological name :EXOC1
  
Synonyms : EXOC1 / exocyst complex component 1 / Q9NV70
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q12
Gene start: 55853616
Gene end: 55905034
  
Corresponding Affymetrix probe sets: 222127_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000334431
Ensembl peptide - ENSP00000370695
Ensembl peptide - ENSP00000326514
NCBI entrez gene - 55763     See in Manteia.
OMIM - 607879
RefSeq - XM_017008407
RefSeq - NM_178237
RefSeq - XM_005265747
RefSeq - XM_005265748
RefSeq - XM_005265750
RefSeq - XM_017008405
RefSeq - XM_017008406
RefSeq - NM_001024924
RefSeq - NM_018261
RefSeq Peptide - NP_839955
RefSeq Peptide - NP_001020095
RefSeq Peptide - NP_060731
swissprot - A0A024RDA9
swissprot - Q9NV70
swissprot - A0A024RDA1
Ensembl - ENSG00000090989
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 exoc1ENSDARG00000043019Danio rerio
 EXOC1ENSGALG00000013778Gallus gallus
 Exoc1ENSMUSG00000036435Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8NFX7 / STXBP6 / syntaxin binding protein 6ENSG000001689526
EXOC1L / exocyst complex component 1 likeENSG000002508215


Protein motifs (from Interpro)
Interpro ID Name
 IPR019160  Exocyst complex component Sec3, C-terminal
 IPR028258  Exocyst complex component Sec3, PIP2-binding N-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006887 exocytosis IBA
 biological_processGO:0006893 Golgi to plasma membrane transport IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016241 regulation of macroautophagy TAS
 biological_processGO:0048015 phosphatidylinositol-mediated signaling IDA
 biological_processGO:0050714 positive regulation of protein secretion IMP
 biological_processGO:0051601 exocyst localization IBA
 biological_processGO:0051607 defense response to virus IEA
 cellular_componentGO:0000145 exocyst IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0090543 Flemming body IEA
 cellular_componentGO:0098592 cytoplasmic side of apical plasma membrane IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IBA
 molecular_functionGO:0017049 GTP-Rho binding IBA


Pathways (from Reactome)
Pathway description
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Insulin processing
VxPx cargo-targeting to cilium


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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