ENSG00000100078


Homo sapiens

Features
Gene ID: ENSG00000100078
  
Biological name :PLA2G3
  
Synonyms : phospholipase A2 group III / PLA2G3 / Q9NZ20
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q12.2
Gene start: 31134809
Gene end: 31140607
  
Corresponding Affymetrix probe sets: 220780_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000215885
NCBI entrez gene - 50487     See in Manteia.
OMIM - 611651
RefSeq - XM_011530205
RefSeq - NM_015715
RefSeq - XM_011530204
RefSeq Peptide - NP_056530
swissprot - Q9NZ20
Ensembl - ENSG00000100078
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CU459012.1ENSDARG00000098989Danio rerio
 zgc:123275ENSDARG00000008948Danio rerio
 ENSGALG00000030512Gallus gallus
 Pla2g3ENSMUSG00000034579Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PROCA1 / Q8NCQ7 / protein interacting with cyclin A1ENSG0000016752511


Protein motifs (from Interpro)
Interpro ID Name
 IPR016090  Phospholipase A2 domain
 IPR033113  Phospholipase A2, histidine active site
 IPR036444  Phospholipase A2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001675 acrosome assembly IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006644 phospholipid metabolic process TAS
 biological_processGO:0007288 sperm axoneme assembly IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0019372 lipoxygenase pathway IEA
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0036148 phosphatidylglycerol acyl-chain remodeling TAS
 biological_processGO:0036151 phosphatidylcholine acyl-chain remodeling TAS
 biological_processGO:0036152 phosphatidylethanolamine acyl-chain remodeling TAS
 biological_processGO:0043303 mast cell degranulation IEA
 biological_processGO:0046470 phosphatidylcholine metabolic process IEA
 biological_processGO:0048468 cell development IEA
 biological_processGO:0050482 arachidonic acid secretion IEA
 biological_processGO:0060271 cilium assembly IMP
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005814 centriole IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0042629 mast cell granule IEA
 molecular_functionGO:0004623 phospholipase A2 activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047498 calcium-dependent phospholipase A2 activity TAS
 molecular_functionGO:0102567 phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) IEA
 molecular_functionGO:0102568 phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) IEA


Pathways (from Reactome)
Pathway description
Acyl chain remodelling of PC
Acyl chain remodelling of PE
Acyl chain remodelling of PG


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr