ENSG00000100129


Homo sapiens

Features
Gene ID: ENSG00000100129
  
Biological name :EIF3L
  
Synonyms : EIF3L / eukaryotic translation initiation factor 3 subunit L / Q9Y262
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.1
Gene start: 37848868
Gene end: 37889407
  
Corresponding Affymetrix probe sets: 217719_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000398176
Ensembl peptide - ENSP00000485663
Ensembl peptide - ENSP00000416892
Ensembl peptide - ENSP00000412349
Ensembl peptide - ENSP00000410576
Ensembl peptide - ENSP00000371099
Ensembl peptide - ENSP00000384634
Ensembl peptide - ENSP00000390271
Ensembl peptide - ENSP00000393822
NCBI entrez gene - 51386     See in Manteia.
RefSeq - XM_017028814
RefSeq - NM_001242923
RefSeq - NM_016091
RefSeq - XM_005261625
RefSeq - XM_006724260
RefSeq Peptide - NP_001229852
RefSeq Peptide - NP_057175
swissprot - Q9Y262
swissprot - C9K0Q7
swissprot - C9JHP4
swissprot - B0QY90
swissprot - B0QY89
swissprot - H7C133
swissprot - H0Y7E6
swissprot - H7C3A0
Ensembl - ENSG00000100129
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q7T2A5ENSDARG00000101082Danio rerio
 EIF3LENSGALG00000012296Gallus gallus
 Eif3lENSMUSG00000033047Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR019382  Translation initiation factor 3 complex subunit L


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001732 formation of cytoplasmic translation initiation complex IEA
 biological_processGO:0002183 cytoplasmic translational initiation IEA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation TAS
 biological_processGO:0075525 viral translational termination-reinitiation IDA
 cellular_componentGO:0001650 fibrillar center IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005852 eukaryotic translation initiation factor 3 complex IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016282 eukaryotic 43S preinitiation complex IEA
 cellular_componentGO:0033290 eukaryotic 48S preinitiation complex IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003743 translation initiation factor activity IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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