ENSG00000100206


Homo sapiens

Features
Gene ID: ENSG00000100206
  
Biological name :DMC1
  
Synonyms : DMC1 / DNA meiotic recombinase 1 / Q14565
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q13.1
Gene start: 38518949
Gene end: 38570286
  
Corresponding Affymetrix probe sets: 208382_s_at (Human Genome U133 Plus 2.0 Array)   208386_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000477737
Ensembl peptide - ENSP00000391385
Ensembl peptide - ENSP00000410808
Ensembl peptide - ENSP00000412703
Ensembl peptide - ENSP00000216024
NCBI entrez gene - 11144     See in Manteia.
OMIM - 602721
RefSeq - XM_017028542
RefSeq - NM_007068
RefSeq - XM_006724112
RefSeq - XM_011529834
RefSeq - XM_011529835
RefSeq - XM_011529837
RefSeq - XM_011529838
RefSeq - NM_001278208
RefSeq Peptide - NP_001265137
RefSeq Peptide - NP_008999
swissprot - B0QYE1
swissprot - Q8IYL1
swissprot - B0QYE0
swissprot - Q14565
Ensembl - ENSG00000100206
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dmc1ENSDARG00000055883Danio rerio
 DMC1ENSGALG00000012236Gallus gallus
 Dmc1ENSMUSG00000022429Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR010995  DNA repair Rad51/transcription factor NusA, alpha-helical
 IPR011940  Meiotic recombinase Dmc1
 IPR013632  DNA recombination and repair protein Rad51-like, C-terminal
 IPR016467  DNA recombination and repair protein, RecA-like
 IPR020587  DNA recombination and repair protein RecA, monomer-monomer interface
 IPR020588  DNA recombination and repair protein RecA-like, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR033925  Rad51/DMC1/RadA


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000730 DNA recombinase assembly IBA
 biological_processGO:0001541 ovarian follicle development IEA
 biological_processGO:0001556 oocyte maturation IEA
 biological_processGO:0006259 DNA metabolic process IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006312 mitotic recombination IBA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007129 synapsis IEA
 biological_processGO:0007131 reciprocal meiotic recombination IBA
 biological_processGO:0007141 male meiosis I IEA
 biological_processGO:0007276 gamete generation IEA
 biological_processGO:0007283 spermatogenesis TAS
 biological_processGO:0007286 spermatid development IEA
 biological_processGO:0007292 female gamete generation TAS
 biological_processGO:0010212 response to ionizing radiation IBA
 biological_processGO:0042148 strand invasion IBA
 biological_processGO:0051321 meiotic cell cycle TAS
 biological_processGO:0070192 chromosome organization involved in meiotic cell cycle IBA
 cellular_componentGO:0000781 chromosome, telomeric region IEA
 cellular_componentGO:0000794 condensed nuclear chromosome IBA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IBA
 cellular_componentGO:0005694 chromosome ISS
 molecular_functionGO:0000150 recombinase activity IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000400 four-way junction DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IBA
 molecular_functionGO:0003697 single-stranded DNA binding IBA
 molecular_functionGO:0004520 endodeoxyribonuclease activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008094 DNA-dependent ATPase activity IEA


Pathways (from Reactome)
Pathway description
Meiotic recombination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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