ENSG00000100294


Homo sapiens

Features
Gene ID: ENSG00000100294
  
Biological name :MCAT
  
Synonyms : malonyl-CoA-acyl carrier protein transacylase / MCAT / Q8IVS2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q13.2
Gene start: 43132206
Gene end: 43143394
  
Corresponding Affymetrix probe sets: 213132_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000290429
Ensembl peptide - ENSP00000331306
Ensembl peptide - ENSP00000477216
NCBI entrez gene - 27349     See in Manteia.
OMIM - 614479
RefSeq - XM_011530156
RefSeq - NM_014507
RefSeq - NM_173467
RefSeq Peptide - NP_775738
RefSeq Peptide - NP_055322
swissprot - Q8IVS2
swissprot - V9GYY6
Ensembl - ENSG00000100294
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mcatENSDARG00000016613Danio rerio
 mcatENSDARG00000096473Danio rerio
 MCATENSGALG00000034275Gallus gallus
 McatENSMUSG00000048755Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR014043  Acyl transferase
 IPR016035  Acyl transferase/acyl hydrolase/lysophospholipase
 IPR016036  Malonyl-CoA ACP transacylase, ACP-binding
 IPR020801  Polyketide synthase, acyl transferase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0006635 fatty acid beta-oxidation TAS
 biological_processGO:0008152 metabolic process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix TAS
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0004312 fatty acid synthase activity IDA
 molecular_functionGO:0004314 [acyl-carrier-protein] S-malonyltransferase activity TAS
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Mitochondrial Fatty Acid Beta-Oxidation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000004779 O14561 / NDUFAB1 / NADH:ubiquinone oxidoreductase subunit AB1  / reaction






 

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contact: otassy@igbmc.fr