ENSG00000100526


Homo sapiens

Features
Gene ID: ENSG00000100526
  
Biological name :CDKN3
  
Synonyms : CDKN3 / cyclin dependent kinase inhibitor 3 / Q16667
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q22.2
Gene start: 54396849
Gene end: 54420218
  
Corresponding Affymetrix probe sets: 1555758_a_at (Human Genome U133 Plus 2.0 Array)   209714_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000445572
Ensembl peptide - ENSP00000480289
Ensembl peptide - ENSP00000479875
Ensembl peptide - ENSP00000450711
Ensembl peptide - ENSP00000335357
Ensembl peptide - ENSP00000378944
Ensembl peptide - ENSP00000396451
Ensembl peptide - ENSP00000415333
Ensembl peptide - ENSP00000440404
NCBI entrez gene - 1033     See in Manteia.
OMIM - 123832
RefSeq - NM_005192
RefSeq - XM_011536353
RefSeq - NM_001130851
RefSeq Peptide - NP_001317102
RefSeq Peptide - NP_001124323
RefSeq Peptide - NP_005183
swissprot - Q16667
swissprot - H7C0S3
swissprot - A0A087WW25
swissprot - F5H232
swissprot - F8WD24
swissprot - G3V1K6
swissprot - G3V2J7
swissprot - A0A087WWK3
Ensembl - ENSG00000100526
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdkn3ENSDARG00000039130Danio rerio
 CDKN3ENSGALG00000012220Gallus gallus
 Cdkn3ENSMUSG00000037628Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR008425  Cyclin-dependent kinase inhibitor 3
 IPR022778  CDKN3 domain
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity TAS
 biological_processGO:0000082 G1/S transition of mitotic cell cycle TAS
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007050 cell cycle arrest IDA
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IDA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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