ENSG00000100604


Homo sapiens

Features
Gene ID: ENSG00000100604
  
Biological name :CHGA
  
Synonyms : CHGA / chromogranin A / P10645
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q32.12
Gene start: 92923080
Gene end: 92935293
  
Corresponding Affymetrix probe sets: 204697_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000216492
Ensembl peptide - ENSP00000334023
Ensembl peptide - ENSP00000450801
NCBI entrez gene - 1113     See in Manteia.
OMIM - 118910
RefSeq - XM_011536370
RefSeq - NM_001275
RefSeq - NM_001301690
RefSeq Peptide - NP_001266
RefSeq Peptide - NP_001288619
swissprot - G3V2Q7
swissprot - G5E968
swissprot - P10645
Ensembl - ENSG00000100604
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chgaENSDARG00000008829Danio rerio
 CHGAENSGALG00000010820Gallus gallus
 ChgaENSMUSG00000021194Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001819  Chromogranin A/B
 IPR001990  Chromogranin A/B/C
 IPR018054  Chromogranin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002026 regulation of the force of heart contraction ISS
 biological_processGO:0002551 mast cell chemotaxis IDA
 biological_processGO:0006996 organelle organization ISS
 biological_processGO:0008217 regulation of blood pressure TAS
 biological_processGO:0019730 antimicrobial humoral response TAS
 biological_processGO:0030816 obsolete positive regulation of cAMP metabolic process ISS
 biological_processGO:0031640 killing of cells of other organism IEA
 biological_processGO:0032762 mast cell cytokine production IDA
 biological_processGO:0033604 negative regulation of catecholamine secretion IDA
 biological_processGO:0042742 defense response to bacterium IEA
 biological_processGO:0043303 mast cell degranulation IDA
 biological_processGO:0045087 innate immune response NAS
 biological_processGO:0045576 mast cell activation IDA
 biological_processGO:0050829 defense response to Gram-negative bacterium IDA
 biological_processGO:0050830 defense response to Gram-positive bacterium IDA
 biological_processGO:0050832 defense response to fungus IEA
 biological_processGO:0060452 positive regulation of cardiac muscle contraction ISS
 biological_processGO:0086030 adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation ISS
 biological_processGO:0097756 negative regulation of blood vessel diameter ISS
 biological_processGO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway ISS
 biological_processGO:1901215 negative regulation of neuron death ISS
 biological_processGO:1901899 positive regulation of relaxation of cardiac muscle ISS
 biological_processGO:2000707 positive regulation of dense core granule biogenesis IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030133 transport vesicle IEA
 cellular_componentGO:0030141 secretory granule IEA
 cellular_componentGO:0030658 transport vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0042583 chromaffin granule ISS
 cellular_componentGO:0042629 mast cell granule IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA


Pathways (from Reactome)
Pathway description
Antimicrobial peptides


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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