ENSG00000100721


Homo sapiens

Features
Gene ID: ENSG00000100721
  
Biological name :TCL1A
  
Synonyms : P56279 / T cell leukemia/lymphoma 1A / TCL1A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q32.13
Gene start: 95709967
Gene end: 95714196
  
Corresponding Affymetrix probe sets: 209995_s_at (Human Genome U133 Plus 2.0 Array)   39318_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000451506
Ensembl peptide - ENSP00000451973
Ensembl peptide - ENSP00000452028
Ensembl peptide - ENSP00000385036
Ensembl peptide - ENSP00000450496
Ensembl peptide - ENSP00000450701
Ensembl peptide - ENSP00000450997
Ensembl peptide - ENSP00000451322
NCBI entrez gene - 8115     See in Manteia.
OMIM - 186960
RefSeq - NM_021966
RefSeq - XM_017021677
RefSeq - XM_017021676
RefSeq - NM_001098725
RefSeq Peptide - NP_001092195
RefSeq Peptide - NP_068801
swissprot - G3V4T4
swissprot - P56279
swissprot - H0YJR9
swissprot - A0A024R6G5
Ensembl - ENSG00000100721
  
Related genetic diseases (OMIM): 186960 - Leukemia/lymphoma, T-cell
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000038681Gallus gallus
 Tcl1ENSMUSG00000041359Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MTCP1 / P56278 / mature T cell proliferation 1ENSG0000021482735
TCL1B / O95988 / T cell leukemia/lymphoma 1BENSG0000021323129


Protein motifs (from Interpro)
Interpro ID Name
 IPR004832  TCL1/MTCP1
 IPR036672  TCL1/MTCP1 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0010918 positive regulation of mitochondrial membrane potential IDA
 biological_processGO:0032461 positive regulation of protein oligomerization IDA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IMP
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0070207 protein homotrimerization IDA
 biological_processGO:0071356 cellular response to tumor necrosis factor IDA
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0032991 protein-containing complex IMP
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0042802 identical protein binding IDA
 molecular_functionGO:0043539 protein serine/threonine kinase activator activity IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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