ENSG00000101152


Homo sapiens

Features
Gene ID: ENSG00000101152
  
Biological name :DNAJC5
  
Synonyms : DNAJC5 / DnaJ heat shock protein family (Hsp40) member C5 / Q9H3Z4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q13.33
Gene start: 63895182
Gene end: 63936031
  
Corresponding Affymetrix probe sets: 224611_s_at (Human Genome U133 Plus 2.0 Array)   224612_s_at (Human Genome U133 Plus 2.0 Array)   224613_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000354111
Ensembl peptide - ENSP00000434744
NCBI entrez gene - 80331     See in Manteia.
OMIM - 611203
RefSeq - XM_011529049
RefSeq - NM_025219
RefSeq - XM_011529048
RefSeq Peptide - NP_079495
swissprot - Q9H3Z4
Ensembl - ENSG00000101152
  
Related genetic diseases (OMIM): 162350 - Ceroid lipofuscinosis, neuronal, 4, Parry type, 162350
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnajc5aaENSDARG00000042948Danio rerio
 dnajc5abENSDARG00000004836Danio rerio
 DNAJC5ENSGALG00000035378Gallus gallus
 Dnajc5ENSMUSG00000000826Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UF47 / DNAJC5B / DnaJ heat shock protein family (Hsp40) member C5 betaENSG0000014757067
Q8N7S2 / DNAJC5G / DnaJ heat shock protein family (Hsp40) member C5 gammaENSG0000016379342
Q8TBM8 / DNAJB14 / DnaJ heat shock protein family (Hsp40) member B14ENSG0000016403128
Q9NXW2 / DNAJB12 / DnaJ heat shock protein family (Hsp40) member B12ENSG0000014871927
Q9H819 / DNAJC18 / DnaJ heat shock protein family (Hsp40) member C18ENSG0000017046427


Protein motifs (from Interpro)
Interpro ID Name
 IPR001623  DnaJ domain
 IPR018253  DnaJ domain, conserved site
 IPR036869  Chaperone J-domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006887 exocytosis NAS
 biological_processGO:0007269 neurotransmitter secretion TAS
 biological_processGO:0016079 synaptic vesicle exocytosis TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0045055 regulated exocytosis TAS
 cellular_componentGO:0005739 mitochondrion HDA
 cellular_componentGO:0005765 lysosomal membrane HDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0035577 azurophil granule membrane TAS
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0043195 terminal bouton IEA
 cellular_componentGO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0043008 ATP-dependent protein binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
GABA synthesis, release, reuptake and degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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