ENSG00000101265


Homo sapiens

Features
Gene ID: ENSG00000101265
  
Biological name :RASSF2
  
Synonyms : P50749 / Ras association domain family member 2 / RASSF2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: p13
Gene start: 4780023
Gene end: 4823645
  
Corresponding Affymetrix probe sets: 203185_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000368684
Ensembl peptide - ENSP00000368710
NCBI entrez gene - 9770     See in Manteia.
OMIM - 609492
RefSeq - XM_017028153
RefSeq - NM_014737
RefSeq - NM_170774
RefSeq - XM_017028150
RefSeq - XM_017028151
RefSeq - XM_017028152
RefSeq - XM_005260895
RefSeq - XM_011529410
RefSeq - XM_011529411
RefSeq - XM_011529412
RefSeq - XM_017028149
RefSeq Peptide - NP_739580
RefSeq Peptide - NP_055552
swissprot - P50749
Ensembl - ENSG00000101265
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rassf2aENSDARG00000029865Danio rerio
 rassf2bENSDARG00000044044Danio rerio
 RASSF2ENSGALG00000030432Gallus gallus
 Q8BMS9ENSMUSG00000027339Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9H2L5 / RASSF4 / Ras association domain family member 4ENSG0000010755155
Q6ZTQ3 / RASSF6 / Ras association domain family member 6ENSG0000016943536


Protein motifs (from Interpro)
Interpro ID Name
 IPR000159  Ras-associating (RA) domain
 IPR011524  SARAH domain
 IPR029071  Ubiquitin-like domain superfamily
 IPR033614  C-terminal RASSF family
 IPR033618  Ras association domain-containing protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development IEA
 biological_processGO:0001503 ossification IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0031954 positive regulation of protein autophosphorylation IDA
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation IDA
 biological_processGO:0038168 epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process IDA
 biological_processGO:0045667 regulation of osteoblast differentiation IEA
 biological_processGO:0045670 regulation of osteoclast differentiation IEA
 biological_processGO:0045860 positive regulation of protein kinase activity IDA
 biological_processGO:0046330 positive regulation of JNK cascade IDA
 biological_processGO:0046849 bone remodeling IEA
 biological_processGO:0048872 homeostasis of number of cells IEA
 biological_processGO:0050821 protein stabilization IMP
 biological_processGO:1901222 regulation of NIK/NF-kappaB signaling IEA
 biological_processGO:1901223 negative regulation of NIK/NF-kappaB signaling IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0004672 protein kinase activity IGI
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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