ENSG00000101323


Homo sapiens

Features
Gene ID: ENSG00000101323
  
Biological name :HAO1
  
Synonyms : HAO1 / hydroxyacid oxidase 1 / Q9UJM8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: p12.3
Gene start: 7882981
Gene end: 7940474
  
Corresponding Affymetrix probe sets: 220224_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000368066
NCBI entrez gene - 54363     See in Manteia.
OMIM - 605023
RefSeq - NM_017545
RefSeq Peptide - NP_060015
swissprot - A8K058
swissprot - Q9UJM8
Ensembl - ENSG00000101323
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hao1ENSDARG00000024160Danio rerio
 HAO1ENSGALG00000008845Gallus gallus
 Hao1ENSMUSG00000027261Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HAO2 / Q9NYQ3 / hydroxyacid oxidase 2ENSG0000011688244


Protein motifs (from Interpro)
Interpro ID Name
 IPR000262  FMN-dependent dehydrogenase
 IPR008259  FMN-dependent alpha-hydroxy acid dehydrogenase, active site
 IPR012133  Alpha-hydroxy acid dehydrogenase, FMN-dependent
 IPR013785  Aldolase-type TIM barrel
 IPR037396  FMN hydroxy acid dehydrogenase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001561 fatty acid alpha-oxidation IDA
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0034641 cellular nitrogen compound metabolic process TAS
 biological_processGO:0046296 glycolate catabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0005782 peroxisomal matrix TAS
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003973 (S)-2-hydroxy-acid oxidase activity IDA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0008891 glycolate oxidase activity EXP
 molecular_functionGO:0010181 FMN binding IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0047969 glyoxylate oxidase activity TAS
 molecular_functionGO:0052852 very-long-chain-(S)-2-hydroxy-acid oxidase activity IEA
 molecular_functionGO:0052853 long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity IEA
 molecular_functionGO:0052854 medium-chain-(S)-2-hydroxy-acid oxidase activity IEA


Pathways (from Reactome)
Pathway description
Glyoxylate metabolism and glycine degradation
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000101323 HAO1 / Q9UJM8 / hydroxyacid oxidase 1  / complex






 

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