ENSG00000101624


Homo sapiens

Features
Gene ID: ENSG00000101624
  
Biological name :CEP76
  
Synonyms : centrosomal protein 76 / CEP76 / Q8TAP6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: -1
Band: p11.21
Gene start: 12661833
Gene end: 12702777
  
Corresponding Affymetrix probe sets: 219311_at (Human Genome U133 Plus 2.0 Array)   52285_f_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467224
Ensembl peptide - ENSP00000467361
Ensembl peptide - ENSP00000262127
Ensembl peptide - ENSP00000403074
Ensembl peptide - ENSP00000464760
Ensembl peptide - ENSP00000464911
Ensembl peptide - ENSP00000466689
Ensembl peptide - ENSP00000466833
NCBI entrez gene - 79959     See in Manteia.
RefSeq - XM_017025987
RefSeq - NM_024899
RefSeq - XM_005258149
RefSeq - XM_017025981
RefSeq - XM_017025982
RefSeq - XM_017025983
RefSeq - XM_017025984
RefSeq - XM_017025985
RefSeq - XM_017025986
RefSeq - NM_001271989
RefSeq Peptide - NP_001258918
RefSeq Peptide - NP_079175
swissprot - K7EP44
swissprot - K7EPF5
swissprot - K7EII2
swissprot - B4DP81
swissprot - Q8TAP6
swissprot - K7EIV8
Ensembl - ENSG00000101624
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cep76ENSDARG00000058319Danio rerio
 ENSGALG00000013858Gallus gallus
 Cep76ENSMUSG00000073542Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR028926  CEP76, C2 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle TAS
 biological_processGO:0010389 regulation of G2/M transition of mitotic cell cycle TAS
 biological_processGO:0046599 regulation of centriole replication IMP
 biological_processGO:0097711 ciliary basal body-plasma membrane docking TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005814 centriole IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr