ENSMUSG00000073542


Mus musculus

Features
Gene ID: ENSMUSG00000073542
  
Biological name :Cep76
  
Synonyms : Centrosomal protein of 76 kDa / Cep76 / Q0VEJ0
  
Possible biological names infered from orthology : centrosomal protein 76 / Q8TAP6
  
Species: Mus musculus
  
Chr. number: 18
Strand: -1
Band: E1
Gene start: 67617397
Gene end: 67641336
  
Corresponding Affymetrix probe sets: 10459576 (MoGene1.0st)   1437209_at (Mouse Genome 430 2.0 Array)   1437254_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000095149
NCBI entrez gene - 225659     See in Manteia.
MGI - MGI:1923401
RefSeq - NM_001081073
RefSeq - XM_006525899
RefSeq Peptide - NP_001074542
swissprot - Q0VEJ0
Ensembl - ENSMUSG00000073542
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cep76ENSDARG00000058319Danio rerio
 ENSGALG00000013858Gallus gallus
 CEP76ENSG00000101624Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR028926  CEP76, C2 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0046599 regulation of centriole replication IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005814 centriole ISS
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000689 abnormal spleen morphology "atypical structure of the organ that functions to filter blood and to store red corpuscles and platelets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:27463]
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Allelic Composition: Cdkn1atm1.1(KOMP)Vlcg/Cdkn1atm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cdkn1atm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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