ENSG00000101856


Homo sapiens

Features
Gene ID: ENSG00000101856
  
Biological name :PGRMC1
  
Synonyms : O00264 / PGRMC1 / progesterone receptor membrane component 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: q24
Gene start: 119236245
Gene end: 119244466
  
Corresponding Affymetrix probe sets: 201120_s_at (Human Genome U133 Plus 2.0 Array)   201121_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000217971
Ensembl peptide - ENSP00000442821
NCBI entrez gene - 10857     See in Manteia.
OMIM - 300435
RefSeq - NM_006667
RefSeq - NM_001282621
RefSeq Peptide - NP_001269550
RefSeq Peptide - NP_006658
swissprot - O00264
swissprot - Q6IB11
Ensembl - ENSG00000101856
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pgrmc1ENSDARG00000054172Danio rerio
 PGRMC1ENSGALG00000020260Gallus gallus
 O55022ENSMUSG00000006373Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O15173 / PGRMC2 / progesterone receptor membrane component 2ENSG0000016404050


Protein motifs (from Interpro)
Interpro ID Name
 IPR001199  Cytochrome b5-like heme/steroid binding domain
 IPR036400  Cytochrome b5-like heme/steroid binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043312 neutrophil degranulation TAS
 cellular_componentGO:0005783 endoplasmic reticulum TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030868 smooth endoplasmic reticulum membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0043005 neuron projection ISS
 cellular_componentGO:0043025 neuronal cell body ISS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0044297 cell body ISS
 cellular_componentGO:0045202 synapse ISS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0106003 amyloid-beta complex ISS
 molecular_functionGO:0005496 steroid binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0020037 heme binding IBA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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