ENSG00000102699


Homo sapiens

Features
Gene ID: ENSG00000102699
  
Biological name :PARP4
  
Synonyms : PARP4 / poly(ADP-ribose) polymerase family member 4 / Q9UKK3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q12.12
Gene start: 24420926
Gene end: 24512810
  
Corresponding Affymetrix probe sets: 202239_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000371419
NCBI entrez gene - 143     See in Manteia.
OMIM - 607519
RefSeq - XM_011534932
RefSeq - NM_006437
RefSeq - XM_011534931
RefSeq Peptide - NP_006428
swissprot - Q9UKK3
Ensembl - ENSG00000102699
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 parp4ENSDARG00000069934Danio rerio
 PARP4ENSGALG00000034473Gallus gallus
 Parp4ENSMUSG00000054509Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
VWA5A / O00534 / von Willebrand factor A domain containing 5AENSG0000011000210
Q5TIE3 / VWA5B1 / von Willebrand factor A domain containing 5B1ENSG0000015881610
Q8N398 / VWA5B2 / von Willebrand factor A domain containing 5B2ENSG000001451989


Protein motifs (from Interpro)
Interpro ID Name
 IPR001357  BRCT domain
 IPR002035  von Willebrand factor, type A
 IPR004102  Poly(ADP-ribose) polymerase, regulatory domain
 IPR012317  Poly(ADP-ribose) polymerase, catalytic domain
 IPR013694  VIT domain
 IPR031273  Poly [ADP-ribose] polymerase 4
 IPR036420  BRCT domain superfamily
 IPR036465  von Willebrand factor A-like domain superfamily
 IPR036616  Poly(ADP-ribose) polymerase, regulatory domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair TAS
 biological_processGO:0006464 cellular protein modification process IDA
 biological_processGO:0006471 protein ADP-ribosylation NAS
 biological_processGO:0006954 inflammatory response IMP
 biological_processGO:0006974 cellular response to DNA damage stimulus NAS
 biological_processGO:0008219 cell death IMP
 biological_processGO:0042493 response to drug NAS
 biological_processGO:0051972 regulation of telomerase activity IDA
 cellular_componentGO:0005634 nucleus NAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005876 spindle microtubule IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003950 NAD+ ADP-ribosyltransferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0019899 enzyme binding IDA


Pathways (from Reactome)
Pathway description
Nicotinamide salvaging


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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