ENSMUSG00000054509


Mus musculus

Features
Gene ID: ENSMUSG00000054509
  
Biological name :Parp4
  
Synonyms : Parp4 / poly(ADP-ribose) polymerase family member 4
  
Possible biological names infered from orthology : Q9UKK3
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: C3
Gene start: 56575619
Gene end: 56659794
  
Corresponding Affymetrix probe sets: 10415513 (MoGene1.0st)   1441026_at (Mouse Genome 430 2.0 Array)   1452351_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000124258
NCBI entrez gene - 328417     See in Manteia.
MGI - MGI:2685589
RefSeq - NM_001145978
RefSeq Peptide - NP_001139450
swissprot - E9PYK3
Ensembl - ENSMUSG00000054509
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 parp4ENSDARG00000069934Danio rerio
 PARP4ENSGALG00000034473Gallus gallus
 PARP4ENSG00000102699Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Vwa5a / Q99KC8 / von Willebrand factor A domain containing 5A / O00534*ENSMUSG000000231869
AW551984 / expressed sequence AW551984 / VWA5A* / O00534* / von Willebrand factor A domain containing 5A*ENSMUSG000000381128
Q3UR50 / Vwa5b2 / von Willebrand factor A domain containing 5B2 / Q8N398*ENSMUSG000000466138
A9Z1V5 / Vwa5b1 / von Willebrand factor A domain containing 5B1 / Q5TIE3*ENSMUSG000000287538


Protein motifs (from Interpro)
Interpro ID Name
 IPR001357  BRCT domain
 IPR002035  von Willebrand factor, type A
 IPR004102  Poly(ADP-ribose) polymerase, regulatory domain
 IPR009408  Formin Homology 1
 IPR012317  Poly(ADP-ribose) polymerase, catalytic domain
 IPR013694  VIT domain
 IPR031273  Poly [ADP-ribose] polymerase 4
 IPR036420  BRCT domain superfamily
 IPR036465  von Willebrand factor A-like domain superfamily
 IPR036616  Poly(ADP-ribose) polymerase, regulatory domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006464 cellular protein modification process IEA
 biological_processGO:0006471 protein ADP-ribosylation IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0008219 cell death IEA
 biological_processGO:0051972 regulation of telomerase activity IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle TAS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005876 spindle microtubule IEA
 molecular_functionGO:0003950 NAD+ ADP-ribosyltransferase activity ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0019899 enzyme binding IEA


Pathways (from Reactome)
Pathway description
Nicotinamide salvaging


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Fmn1tm1.1Zlr/Fmn1tm1.1Zlr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Parp4tm1Leah/Parp4tm1Leah,Tep1tm1Leah/Tep1tm1Leah
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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