ENSG00000102854


Homo sapiens

Features
Gene ID: ENSG00000102854
  
Biological name :MSLN
  
Synonyms : mesothelin / MSLN / Q13421
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p13.3
Gene start: 760762
Gene end: 768865
  
Corresponding Affymetrix probe sets: 204885_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000458003
Ensembl peptide - ENSP00000456702
Ensembl peptide - ENSP00000457847
Ensembl peptide - ENSP00000372313
Ensembl peptide - ENSP00000442965
Ensembl peptide - ENSP00000454295
Ensembl peptide - ENSP00000456008
Ensembl peptide - ENSP00000456132
NCBI entrez gene - 10232     See in Manteia.
OMIM - 601051
RefSeq - XM_017022858
RefSeq - NM_013404
RefSeq - XM_005255034
RefSeq - XM_011522348
RefSeq - XM_017022853
RefSeq - XM_017022854
RefSeq - XM_017022855
RefSeq - XM_017022856
RefSeq - XM_017022857
RefSeq - NM_001177355
RefSeq - NM_005823
RefSeq Peptide - NP_037536
RefSeq Peptide - NP_001170826
RefSeq Peptide - NP_005814
swissprot - H3BR90
swissprot - H3BMA1
swissprot - Q13421
swissprot - H3BUX1
swissprot - H3BV92
Ensembl - ENSG00000102854
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01052573.1ENSDARG00000100739Danio rerio
 mslnaENSDARG00000098949Danio rerio
 si:ch211-188p14.4ENSDARG00000100190Danio rerio
 si:ch211-188p14.5ENSDARG00000099024Danio rerio
 ENSGALG00000005349Gallus gallus
 MslnENSMUSG00000063011Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MSLNL / Q96KJ4 / mesothelin-likeENSG0000016200623


Protein motifs (from Interpro)
Interpro ID Name
 IPR010335  Mesothelin
 IPR026664  Stereocilin-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006501 C-terminal protein lipidation TAS
 biological_processGO:0007155 cell adhesion NAS
 biological_processGO:0007160 cell-matrix adhesion IBA
 biological_processGO:0031016 pancreas development IEA
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0044267 cellular protein metabolic process TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane NAS
 cellular_componentGO:0031225 anchored component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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