ENSMUSG00000063011


Mus musculus

Features
Gene ID: ENSMUSG00000063011
  
Biological name :Msln
  
Synonyms : Msln / Mus musculus mesothelin (Msln), transcript variant 1, mRNA. / Q61468
  
Possible biological names infered from orthology : mesothelin / Q13421
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: A3.3
Gene start: 25748614
Gene end: 25754327
  
Corresponding Affymetrix probe sets: 10449000 (MoGene1.0st)   1460238_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000075279
NCBI entrez gene - 56047     See in Manteia.
MGI - MGI:1888992
RefSeq - XM_006524650
RefSeq - NM_001356286
RefSeq - NM_018857
RefSeq - XM_006524649
RefSeq Peptide - NP_001343215
RefSeq Peptide - NP_061345
swissprot - Q61468
Ensembl - ENSMUSG00000063011
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01052573.1ENSDARG00000100739Danio rerio
 mslnaENSDARG00000098949Danio rerio
 si:ch211-188p14.4ENSDARG00000100190Danio rerio
 si:ch211-188p14.5ENSDARG00000099024Danio rerio
 ENSGALG00000005349Gallus gallus
 MSLNENSG00000102854Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mslnl / Q8C160 / Mesothelin-like protein / Q96KJ4* / mesothelin-like*ENSMUSG0000004106226


Protein motifs (from Interpro)
Interpro ID Name
 IPR010335  Mesothelin
 IPR026664  Stereocilin-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IBA
 biological_processGO:0031016 pancreas development IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Irs2tm1With/Irs2tm1With,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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