ENSG00000103018


Homo sapiens

Features
Gene ID: ENSG00000103018
  
Biological name :CYB5B
  
Synonyms : CYB5B / cytochrome b5 type B / O43169
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q22.1
Gene start: 69424525
Gene end: 69466266
  
Corresponding Affymetrix probe sets: 201633_s_at (Human Genome U133 Plus 2.0 Array)   201634_s_at (Human Genome U133 Plus 2.0 Array)   227382_at (Human Genome U133 Plus 2.0 Array)   238554_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000457848
Ensembl peptide - ENSP00000464102
Ensembl peptide - ENSP00000308430
Ensembl peptide - ENSP00000421492
Ensembl peptide - ENSP00000423679
NCBI entrez gene - 80777     See in Manteia.
OMIM - 611964
RefSeq - NM_030579
RefSeq Peptide - NP_085056
swissprot - J3KNF8
swissprot - D6RFH4
swissprot - O43169
swissprot - J3QR91
swissprot - H3BUX2
Ensembl - ENSG00000103018
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYB5BENSGALG00000000660Gallus gallus
 Cyb5bENSMUSG00000031924Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CYB5A / P00167 / cytochrome b5 type AENSG0000016634740


Protein motifs (from Interpro)
Interpro ID Name
 IPR001199  Cytochrome b5-like heme/steroid binding domain
 IPR018506  Cytochrome b5, heme-binding site
 IPR023271  Aquaporin-like
 IPR036400  Cytochrome b5-like heme/steroid binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006805 xenobiotic metabolic process TAS
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008047 enzyme activator activity IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Phase I - Functionalization of compounds


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000117791 MARC2 / Q969Z3 / mitochondrial amidoxime reducing component 2  / complex
 ENSG00000186205 MARC1 / Q5VT66 / mitochondrial amidoxime reducing component 1  / complex
 ENSG00000100243 CYB5R3 / P00387 / cytochrome b5 reductase 3  / complex






 

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contact: otassy@igbmc.fr