ENSG00000186205


Homo sapiens

Features
Gene ID: ENSG00000186205
  
Biological name :MARC1
  
Synonyms : MARC1 / mitochondrial amidoxime reducing component 1 / Q5VT66
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q41
Gene start: 220786759
Gene end: 220819657
  
Corresponding Affymetrix probe sets: 218865_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000355877
Ensembl peptide - ENSP00000385327
Ensembl peptide - ENSP00000409634
Ensembl peptide - ENSP00000434522
NCBI entrez gene - 64757     See in Manteia.
OMIM - 614126
RefSeq - XM_017002097
RefSeq - NM_022746
RefSeq - XM_011509900
RefSeq - XM_011509903
RefSeq - XM_011509904
RefSeq - XM_017002096
RefSeq Peptide - NP_073583
swissprot - H7BYZ9
swissprot - H0YDX4
swissprot - Q5VT66
swissprot - X6RIL1
Ensembl - ENSG00000186205
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:110783ENSDARG00000070487Danio rerio
 MARC1ENSGALG00000009453Gallus gallus
 Marc1ENSMUSG00000026621Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MARC2 / Q969Z3 / mitochondrial amidoxime reducing component 2ENSG0000011779164
MOCOS / Q96EN8 / molybdenum cofactor sulfuraseENSG0000007564322


Protein motifs (from Interpro)
Interpro ID Name
 IPR005302  Molybdenum cofactor sulfurase, C-terminal
 IPR005303  MOSC, N-terminal beta barrel
 IPR011037  Pyruvate kinase-like, insert domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006805 xenobiotic metabolic process TAS
 biological_processGO:0042126 nitrate metabolic process IDA
 biological_processGO:0051410 detoxification of nitrogen compound NAS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005741 mitochondrial outer membrane TAS
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0008940 nitrate reductase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0030151 molybdenum ion binding IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0043546 molybdopterin cofactor binding IDA


Pathways (from Reactome)
Pathway description
Phase I - Functionalization of compounds


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000103018 CYB5B / O43169 / cytochrome b5 type B  / complex
 ENSG00000100243 CYB5R3 / P00387 / cytochrome b5 reductase 3  / complex
 ENSG00000117791 MARC2 / Q969Z3 / mitochondrial amidoxime reducing component 2  / complex






 

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