ENSG00000103066


Homo sapiens

Features
Gene ID: ENSG00000103066
  
Biological name :PLA2G15
  
Synonyms : phospholipase A2 group XV / PLA2G15 / Q8NCC3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q22.1
Gene start: 68245304
Gene end: 68261062
  
Corresponding Affymetrix probe sets: 204458_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000454557
Ensembl peptide - ENSP00000457049
Ensembl peptide - ENSP00000457034
Ensembl peptide - ENSP00000455461
Ensembl peptide - ENSP00000219345
Ensembl peptide - ENSP00000393610
Ensembl peptide - ENSP00000394197
Ensembl peptide - ENSP00000454227
NCBI entrez gene - 23659     See in Manteia.
OMIM - 609362
RefSeq - NM_012320
RefSeq - XM_005255886
RefSeq - XM_011522979
RefSeq - XM_011522980
RefSeq Peptide - NP_036452
swissprot - Q8NCC3
swissprot - H3BT70
swissprot - B4DJW4
swissprot - H3BM47
swissprot - H3BMU8
swissprot - H3BPT3
swissprot - B4DPU0
Ensembl - ENSG00000103066
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pla2g15ENSDARG00000103271Danio rerio
 PLA2G15ENSGALG00000041787Gallus gallus
 Q8VEB4ENSMUSG00000031903Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LCAT / P04180 / lecithin-cholesterol acyltransferaseENSG0000021339847


Protein motifs (from Interpro)
Interpro ID Name
 IPR003386  Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006644 phospholipid metabolic process TAS
 biological_processGO:0006650 glycerophospholipid metabolic process IEA
 biological_processGO:0006672 ceramide metabolic process IEA
 biological_processGO:0009062 fatty acid catabolic process TAS
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0034638 phosphatidylcholine catabolic process IEA
 biological_processGO:0046338 phosphatidylethanolamine catabolic process IEA
 biological_processGO:0046470 phosphatidylcholine metabolic process IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005764 lysosome NAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004622 lysophospholipase activity TAS
 molecular_functionGO:0005543 phospholipid binding TAS
 molecular_functionGO:0008374 O-acyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0047499 calcium-independent phospholipase A2 activity TAS


Pathways (from Reactome)
Pathway description
Hydrolysis of LPC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr