ENSG00000103154


Homo sapiens

Features
Gene ID: ENSG00000103154
  
Biological name :NECAB2
  
Synonyms : NECAB2 / N-terminal EF-hand calcium binding protein 2 / Q7Z6G3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q23.3
Gene start: 83968632
Gene end: 84002776
  
Corresponding Affymetrix probe sets: 215005_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000307449
Ensembl peptide - ENSP00000455322
Ensembl peptide - ENSP00000455713
Ensembl peptide - ENSP00000457354
NCBI entrez gene - 54550     See in Manteia.
RefSeq - XM_017023317
RefSeq - NM_019065
RefSeq - XM_011523135
RefSeq Peptide - NP_001316678
RefSeq Peptide - NP_061938
swissprot - Q7Z6G3
swissprot - H3BQC7
swissprot - H3BPH6
Ensembl - ENSG00000103154
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 necab2ENSDARG00000056745Danio rerio
 NECAB2ENSGALG00000003309Gallus gallus
 Necab2ENSMUSG00000031837Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NECAB1 / Q8N987 / N-terminal EF-hand calcium binding protein 1ENSG0000012311938
NECAB3 / Q96P71 / N-terminal EF-hand calcium binding protein 3ENSG0000012596734


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR007138  Antibiotic biosynthesis monooxygenase domain
 IPR011008  Dimeric alpha-beta barrel
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0060168 positive regulation of adenosine receptor signaling pathway IDA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IDA
 biological_processGO:1900451 positive regulation of glutamate receptor signaling pathway IDA
 biological_processGO:1904021 negative regulation of G-protein coupled receptor internalization IDA
 biological_processGO:1905477 positive regulation of protein localization to membrane IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031687 A2A adenosine receptor binding IDA
 molecular_functionGO:0031802 type 5 metabotropic glutamate receptor binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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