ENSMUSG00000031837


Mus musculus

Features
Gene ID: ENSMUSG00000031837
  
Biological name :Necab2
  
Synonyms : Necab2 / N-terminal EF-hand calcium-binding protein 2 / Q91ZP9
  
Possible biological names infered from orthology : Q7Z6G3
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: E1
Gene start: 119446719
Gene end: 119472640
  
Corresponding Affymetrix probe sets: 10575880 (MoGene1.0st)   1418881_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000095966
NCBI entrez gene - 117148     See in Manteia.
MGI - MGI:2152211
RefSeq - XM_017312526
RefSeq - NM_054095
RefSeq - XM_006530583
RefSeq Peptide - NP_473436
swissprot - Q91ZP9
Ensembl - ENSMUSG00000031837
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 necab2ENSDARG00000056745Danio rerio
 NECAB2ENSGALG00000003309Gallus gallus
 NECAB2ENSG00000103154Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Necab1 / Q8BG18 / N-terminal EF-hand calcium-binding protein 1 / Q8N987*ENSMUSG0000004053637
Necab3 / Q9D6J4 / N-terminal EF-hand calcium-binding protein 3 / Q96P71*ENSMUSG0000002748933


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR007138  Antibiotic biosynthesis monooxygenase domain
 IPR011008  Dimeric alpha-beta barrel
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0060168 positive regulation of adenosine receptor signaling pathway IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:1900451 positive regulation of glutamate receptor signaling pathway IEA
 biological_processGO:1904021 negative regulation of G-protein coupled receptor internalization IEA
 biological_processGO:1905477 positive regulation of protein localization to membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0031687 A2A adenosine receptor binding IEA
 molecular_functionGO:0031802 type 5 metabotropic glutamate receptor binding IEA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0006380 abnormal spermatid morphology "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Arhgap35m1Bchd/Arhgap35tm1Jset
Genetic Background: involves: 129S2/SvPas * C3H/HeNCrl * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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