ENSG00000103175


Homo sapiens

Features
Gene ID: ENSG00000103175
  
Biological name :WFDC1
  
Synonyms : Q9HC57 / WAP four-disulfide core domain 1 / WFDC1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q24.1
Gene start: 84294646
Gene end: 84329851
  
Corresponding Affymetrix probe sets: 219478_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000481580
Ensembl peptide - ENSP00000219454
Ensembl peptide - ENSP00000456920
NCBI entrez gene - 58189     See in Manteia.
OMIM - 605322
RefSeq - XM_005256079
RefSeq - NM_001282466
RefSeq - NM_001282467
RefSeq - NM_021197
RefSeq Peptide - NP_001269395
RefSeq Peptide - NP_001269396
RefSeq Peptide - NP_067020
swissprot - Q9HC57
swissprot - A0A087WY77
Ensembl - ENSG00000103175
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wfdc1ENSDARG00000058003Danio rerio
 WFDC1ENSGALG00000005503Gallus gallus
 Wfdc1ENSMUSG00000023336Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008197  WAP-type "four-disulfide core" domain
 IPR036645  Elafin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IBA
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0030308 negative regulation of cell growth NAS
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0061045 negative regulation of wound healing IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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