ENSG00000103375


Homo sapiens

Features
Gene ID: ENSG00000103375
  
Biological name :AQP8
  
Synonyms : AQP8 / aquaporin 8 / O94778
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p12.1
Gene start: 25215731
Gene end: 25228940
  
Corresponding Affymetrix probe sets: 206784_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000454457
Ensembl peptide - ENSP00000219660
NCBI entrez gene - 343     See in Manteia.
OMIM - 603750
RefSeq - XM_011545823
RefSeq - NM_001169
RefSeq - XM_011545822
RefSeq Peptide - NP_001160
swissprot - O94778
swissprot - A0A0C4DGL6
Ensembl - ENSG00000103375
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aqp8a.1ENSDARG00000045141Danio rerio
 Aqp8ENSMUSG00000030762Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AQP5 / P55064 / aquaporin 5ENSG0000016179830
AQP2 / P41181 / aquaporin 2ENSG0000016758029
MIP / P30301 / major intrinsic protein of lens fiberENSG0000013551727
AQP4 / P55087 / aquaporin 4ENSG0000017188526
AQP6 / Q13520 / aquaporin 6ENSG0000008615926
AQP1 / P29972 / aquaporin 1 (Colton blood group)ENSG0000024058324
AC004691.2ENSG0000025042424


Protein motifs (from Interpro)
Interpro ID Name
 IPR000425  Major intrinsic protein
 IPR022357  Major intrinsic protein, conserved site
 IPR023271  Aquaporin-like
 IPR023277  Aquaporin 8
 IPR034294  Aquaporin transporter


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006833 water transport IEA
 biological_processGO:0034220 ion transmembrane transport IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071320 cellular response to cAMP IEP
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0045177 apical part of cell IDA
 molecular_functionGO:0015250 water channel activity TAS
 molecular_functionGO:0015267 channel activity IEA


Pathways (from Reactome)
Pathway description
Detoxification of Reactive Oxygen Species
Passive transport by Aquaporins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000103375 AQP8 / O94778 / aquaporin 8  / complex






 

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