ENSG00000103415


Homo sapiens

Features
Gene ID: ENSG00000103415
  
Biological name :HMOX2
  
Synonyms : heme oxygenase 2 / HMOX2 / P30519
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p13.3
Gene start: 4474690
Gene end: 4510347
  
Corresponding Affymetrix probe sets: 218120_s_at (Human Genome U133 Plus 2.0 Array)   218121_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000477572
Ensembl peptide - ENSP00000461428
Ensembl peptide - ENSP00000484423
Ensembl peptide - ENSP00000484467
Ensembl peptide - ENSP00000219700
Ensembl peptide - ENSP00000381595
Ensembl peptide - ENSP00000385100
Ensembl peptide - ENSP00000391637
Ensembl peptide - ENSP00000394103
Ensembl peptide - ENSP00000458592
Ensembl peptide - ENSP00000458797
Ensembl peptide - ENSP00000458824
Ensembl peptide - ENSP00000459203
Ensembl peptide - ENSP00000459214
Ensembl peptide - ENSP00000459445
Ensembl peptide - ENSP00000460926
Ensembl peptide - ENSP00000460992
NCBI entrez gene - 3163     See in Manteia.
OMIM - 141251
RefSeq - NM_001286267
RefSeq - NM_001127204
RefSeq - NM_001127205
RefSeq - NM_001127206
RefSeq - NM_001286268
RefSeq - NM_001286269
RefSeq - NM_001286270
RefSeq - NM_001286271
RefSeq - NM_002134
RefSeq - XM_011522473
RefSeq - XM_017023196
RefSeq - XM_017023197
RefSeq Peptide - NP_001273199
RefSeq Peptide - NP_001120676
RefSeq Peptide - NP_001120677
RefSeq Peptide - NP_001273200
RefSeq Peptide - NP_002125
RefSeq Peptide - NP_001120678
RefSeq Peptide - NP_001273196
RefSeq Peptide - NP_001273197
RefSeq Peptide - NP_001273198
swissprot - A0A087WT44
swissprot - P30519
swissprot - A0A1B0GXH0
swissprot - I3L159
swissprot - I3L1F5
swissprot - I3L1Y2
swissprot - I3L276
swissprot - I3L463
swissprot - I3L4P8
Ensembl - ENSG00000103415
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hmox2aENSDARG00000114695Danio rerio
 hmox2bENSDARG00000078452Danio rerio
 HMOX2ENSGALG00000007638Gallus gallus
 Hmox2ENSMUSG00000004070Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HMOX1 / P09601 / heme oxygenase 1ENSG0000010029235


Protein motifs (from Interpro)
Interpro ID Name
 IPR002051  Haem oxygenase
 IPR016053  Haem oxygenase-like
 IPR016084  Haem oxygenase-like, multi-helical
 IPR018207  Haem oxygenase conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IDA
 biological_processGO:0006788 heme oxidation IEA
 biological_processGO:0006879 cellular iron ion homeostasis TAS
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0042167 heme catabolic process IBA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0055072 iron ion homeostasis IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004392 heme oxygenase (decyclizing) activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0020037 heme binding IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Heme degradation
Neutrophil degranulation
Iron uptake and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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