ENSG00000103423


Homo sapiens

Features
Gene ID: ENSG00000103423
  
Biological name :DNAJA3
  
Synonyms : DNAJA3 / DnaJ heat shock protein family (Hsp40) member A3 / Q96EY1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p13.3
Gene start: 4425805
Gene end: 4456775
  
Corresponding Affymetrix probe sets: 1554078_s_at (Human Genome U133 Plus 2.0 Array)   205963_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000460358
Ensembl peptide - ENSP00000393970
Ensembl peptide - ENSP00000347445
Ensembl peptide - ENSP00000262375
Ensembl peptide - ENSP00000458868
Ensembl peptide - ENSP00000459088
Ensembl peptide - ENSP00000459098
NCBI entrez gene - 9093     See in Manteia.
OMIM - 608382
RefSeq - NM_001286516
RefSeq - NM_001135110
RefSeq - NM_005147
RefSeq Peptide - NP_001128582
RefSeq Peptide - NP_005138
RefSeq Peptide - NP_001273445
swissprot - Q96EY1
swissprot - I3L1I6
swissprot - I3L1T6
swissprot - I3L1T9
swissprot - I3L3D3
swissprot - Q53G26
Ensembl - ENSG00000103423
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnaja3aENSDARG00000058494Danio rerio
 dnaja3bENSDARG00000102295Danio rerio
 DNAJA3ENSGALG00000007821Gallus gallus
 Dnaja3ENSMUSG00000004069Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9Y2G8 / DNAJC16 / DnaJ heat shock protein family (Hsp40) member C16ENSG0000011613820


Protein motifs (from Interpro)
Interpro ID Name
 IPR001305  Heat shock protein DnaJ, cysteine-rich domain
 IPR001623  DnaJ domain
 IPR002939  Chaperone DnaJ, C-terminal
 IPR008971  HSP40/DnaJ peptide-binding
 IPR012724  Chaperone DnaJ
 IPR018253  DnaJ domain, conserved site
 IPR036410  Heat shock protein DnaJ, cysteine-rich domain superfamily
 IPR036869  Chaperone J-domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006264 mitochondrial DNA replication IEA
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006924 activation-induced cell death of T cells IEA
 biological_processGO:0007005 mitochondrion organization IBA
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0007528 neuromuscular junction development IEA
 biological_processGO:0007569 cell aging IEA
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0009408 response to heat IEA
 biological_processGO:0033077 T cell differentiation in thymus IEA
 biological_processGO:0042102 positive regulation of T cell proliferation IEA
 biological_processGO:0043069 negative regulation of programmed cell death IEA
 biological_processGO:0050790 regulation of catalytic activity IEA
 biological_processGO:0071340 skeletal muscle acetylcholine-gated channel clustering ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005884 actin filament IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019897 extrinsic component of plasma membrane ISS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031594 neuromuscular junction ISS
 cellular_componentGO:0042645 mitochondrial nucleoid IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0030544 Hsp70 protein binding IEA
 molecular_functionGO:0030695 GTPase regulator activity IEA
 molecular_functionGO:0031072 heat shock protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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